Deciphering the Role of Post-Translational Modifications and Cellular Location of Hepatitis Delta Virus (HDV) Antigens in HDV-Mediated Liver Damage in Mice

Deciphering the Role of Post-Translational Modifications and Cellular Location of Hepatitis Delta Virus (HDV) Antigens in HDV-Mediated Liver Damage in Mice

Hepatitis D virus (HDV) infection represents the most severe form of chronic viral hepatitis. We have shown that the delivery of HDV replication-competent genomes to the hepatocytes using adeno-associated virus (AAV-HDV) as gene delivery vehicles offers a unique platform to investigate the molecular...

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Bibliographic Details
Main Authors: Sheila Maestro, Nahia Gomez-Echarte, Gracian Camps, Carla Usai, Cristina Olagüe, Africa Vales, Rafael Aldabe, Gloria Gonzalez-Aseguinolaza
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Viruses
Subjects:
HDV
HDAg post-translational modification
isoprenylation
phosphorylation
ribozyme
intracellular localization: cell and mouse models
Online Access:https://www.mdpi.com/1999-4915/16/3/379

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