Osteoarthitis of Leptin-Deficient ob/ob Mice in Response to Biomechanical Loading in Micro-CT

Osteoarthitis of Leptin-Deficient ob/ob Mice in Response to Biomechanical Loading in Micro-CT

<p>Objective: Mechanotransduction is the mechanism that due to reacting chondrocytes on biomechanical loading of body mass. Higher biomechanical loading lead to increased degeneration of chondrocytes, whereas moderate loading is protecting. This suggests that body fat regulates bone metabolism...

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Bibliographic Details
Main Author:	Hansjoerg Heep, Gero Hilken, Sebastian Hofmeister, Christian Wedemeyer
Format:	Article
Language:	English
Published:	Ivyspring International Publisher 2009-01-01
Series:	International Journal of Biological Sciences
Online Access:	http://www.biolsci.org/v05p0265.htm

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