Neoadjuvant therapy alters the immune microenvironment in pancreatic cancer

Neoadjuvant therapy alters the immune microenvironment in pancreatic cancer

Pancreatic cancer has an exclusive inhibitory tumor microenvironment characterized by a dense mechanical barrier, profound infiltration of immunosuppressive cells, and a lack of penetration of effector T cells, which constitute an important cause for recurrence and metastasis, resistance to chemothe...

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Bibliographic Details
Main Authors: Huiru Zhang, Longyun Ye, Xianjun Yu, Kaizhou Jin, Weiding Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
pancreatic cancer
tumor environment (TME)
immune
immunology
neoadjuvant therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.956984/full

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