Modulation of three key innate immune pathways for the most common retinal degenerative diseases
Abstract This review highlights the role of three key immune pathways in the pathophysiology of major retinal degenerative diseases including diabetic retinopathy, age‐related macular degeneration, and rare retinal dystrophies. We first discuss the mechanisms how loss of retinal homeostasis evokes a...
Main Authors: | Isha Akhtar‐Schäfer, Luping Wang, Tim U Krohne, Heping Xu, Thomas Langmann |
---|---|
Format: | Article |
Language: | English |
Published: |
Springer Nature
2018-10-01
|
Series: | EMBO Molecular Medicine |
Subjects: | |
Online Access: | https://doi.org/10.15252/emmm.201708259 |
Similar Items
-
Microglia in Retinal Degeneration
by: Khalid Rashid, et al.
Published: (2019-08-01) -
The Contribution of Microglia to the Development and Maturation of the Visual System
by: Michael A. Dixon, et al.
Published: (2021-04-01) -
Exploring the pathogenesis of age-related macular degeneration: A review of the interplay between retinal pigment epithelium dysfunction and the innate immune system
by: Josephine H. C. Wong, et al.
Published: (2022-11-01) -
The epididymal immune balance: a key to preserving male fertility
by: Allison Voisin, et al.
Published: (2019-01-01) -
Microglia depletion/repopulation does not affect light-induced retinal degeneration in mice
by: Nils Laudenberg, et al.
Published: (2024-01-01)