The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A Review
Ultrasound is a noninvasive technique that provides real-time imaging with excellent resolution, and several studies demonstrated the potential of ultrasound in acute ischemic stroke monitoring. However, only a few studies were performed using animal models, of which many showed ultrasound to be a s...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-11-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/9/11/1609 |
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| author | Mari Carmen Gómez-de Frutos Fernando Laso-García Iván García-Suárez Luke Diekhorst Laura Otero-Ortega María Alonso de Leciñana Blanca Fuentes Dolores Piniella Gerardo Ruiz-Ares Exuperio Díez-Tejedor María Gutiérrez-Fernández |
| author_facet | Mari Carmen Gómez-de Frutos Fernando Laso-García Iván García-Suárez Luke Diekhorst Laura Otero-Ortega María Alonso de Leciñana Blanca Fuentes Dolores Piniella Gerardo Ruiz-Ares Exuperio Díez-Tejedor María Gutiérrez-Fernández |
| author_sort | Mari Carmen Gómez-de Frutos |
| collection | DOAJ |
| description | Ultrasound is a noninvasive technique that provides real-time imaging with excellent resolution, and several studies demonstrated the potential of ultrasound in acute ischemic stroke monitoring. However, only a few studies were performed using animal models, of which many showed ultrasound to be a safe and effective tool also in therapeutic applications. The full potential of ultrasound application in experimental stroke is yet to be explored to further determine the limitations of this technique and to ensure the accuracy of translational research. This review covers the current status of ultrasound applied to monitoring and treatment in experimental animal models of stroke and examines the safety, limitations, and future perspectives. |
| first_indexed | 2024-03-10T05:41:30Z |
| format | Article |
| id | doaj.art-a97b2f3bfc5b49d49c02ae083691eab1 |
| institution | Directory Open Access Journal |
| issn | 2227-9059 |
| language | English |
| last_indexed | 2024-03-10T05:41:30Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj.art-a97b2f3bfc5b49d49c02ae083691eab12023-11-22T22:30:45ZengMDPI AGBiomedicines2227-90592021-11-01911160910.3390/biomedicines9111609The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A ReviewMari Carmen Gómez-de Frutos0Fernando Laso-García1Iván García-Suárez2Luke Diekhorst3Laura Otero-Ortega4María Alonso de Leciñana5Blanca Fuentes6Dolores Piniella7Gerardo Ruiz-Ares8Exuperio Díez-Tejedor9María Gutiérrez-Fernández10Neurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, La Paz University Hospital, Neuroscience Area of IdiPAZ Health Research Institute, Universidad Autónoma de Madrid, 28046 Madrid, SpainUltrasound is a noninvasive technique that provides real-time imaging with excellent resolution, and several studies demonstrated the potential of ultrasound in acute ischemic stroke monitoring. However, only a few studies were performed using animal models, of which many showed ultrasound to be a safe and effective tool also in therapeutic applications. The full potential of ultrasound application in experimental stroke is yet to be explored to further determine the limitations of this technique and to ensure the accuracy of translational research. This review covers the current status of ultrasound applied to monitoring and treatment in experimental animal models of stroke and examines the safety, limitations, and future perspectives.https://www.mdpi.com/2227-9059/9/11/1609animal modelhemorrhagicischemicstrokeultrasound |
| spellingShingle | Mari Carmen Gómez-de Frutos Fernando Laso-García Iván García-Suárez Luke Diekhorst Laura Otero-Ortega María Alonso de Leciñana Blanca Fuentes Dolores Piniella Gerardo Ruiz-Ares Exuperio Díez-Tejedor María Gutiérrez-Fernández The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A Review Biomedicines animal model hemorrhagic ischemic stroke ultrasound |
| title | The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A Review |
| title_full | The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A Review |
| title_fullStr | The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A Review |
| title_full_unstemmed | The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A Review |
| title_short | The Role of Ultrasound as a Diagnostic and Therapeutic Tool in Experimental Animal Models of Stroke: A Review |
| title_sort | role of ultrasound as a diagnostic and therapeutic tool in experimental animal models of stroke a review |
| topic | animal model hemorrhagic ischemic stroke ultrasound |
| url | https://www.mdpi.com/2227-9059/9/11/1609 |
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