Gastric Cancer Due to Chronic <i>H. pylori</i> Infection: What We Know and Where We Are Going
<i>Helicobacter pylori</i> is an established cause of many gastrointestinal pathologies including peptic ulcer disease, gastritis, and gastric cancer. It is an entity that affects the global population, and its true nature has only been known since the 1980s. Although there is much known...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Diseases |
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| Online Access: | https://www.mdpi.com/2079-9721/10/3/57 |
| _version_ | 1797489346820964352 |
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| author | Patrick Joseph Tempera Mark Michael Omar Tageldin Stephen Hasak |
| author_facet | Patrick Joseph Tempera Mark Michael Omar Tageldin Stephen Hasak |
| author_sort | Patrick Joseph Tempera |
| collection | DOAJ |
| description | <i>Helicobacter pylori</i> is an established cause of many gastrointestinal pathologies including peptic ulcer disease, gastritis, and gastric cancer. It is an entity that affects the global population, and its true nature has only been known since the 1980s. Although there is much known about <i>H. pylori</i> including its pathophysiology, detection, and eradication, resistance to current therapy models is common. This is problematic because untreated or inadequately treated <i>H. pylori</i> increases morbidity and mortality related to gastric cancer and peptic ulcer disease among others. In order to improve the treatment and reduce resistance, there is significant ongoing research identifying new detection and eradication methods for <i>H. pylori</i>. This review aims to highlight what has already been established regarding <i>H. pylori</i>’s epidemiology, pathophysiology, detection, and treatment as well as the most current and novel research involving detection and treatment of <i>H. pylori</i>. |
| first_indexed | 2024-03-10T00:16:11Z |
| format | Article |
| id | doaj.art-a989ae5a50bb46c58558d48846c6c490 |
| institution | Directory Open Access Journal |
| issn | 2079-9721 |
| language | English |
| last_indexed | 2024-03-10T00:16:11Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diseases |
| spelling | doaj.art-a989ae5a50bb46c58558d48846c6c4902023-11-23T15:51:51ZengMDPI AGDiseases2079-97212022-08-011035710.3390/diseases10030057Gastric Cancer Due to Chronic <i>H. pylori</i> Infection: What We Know and Where We Are GoingPatrick Joseph Tempera0Mark Michael1Omar Tageldin2Stephen Hasak3Department of Internal Medicine, Albany Medical Center, Albany, NY 12208, USADepartment of Internal Medicine, Albany Medical Center, Albany, NY 12208, USADepartment of Gastroenterology, Albany Medical Center, Albany, NY 12208, USADepartment of Gastroenterology, Albany Medical Center, Albany, NY 12208, USA<i>Helicobacter pylori</i> is an established cause of many gastrointestinal pathologies including peptic ulcer disease, gastritis, and gastric cancer. It is an entity that affects the global population, and its true nature has only been known since the 1980s. Although there is much known about <i>H. pylori</i> including its pathophysiology, detection, and eradication, resistance to current therapy models is common. This is problematic because untreated or inadequately treated <i>H. pylori</i> increases morbidity and mortality related to gastric cancer and peptic ulcer disease among others. In order to improve the treatment and reduce resistance, there is significant ongoing research identifying new detection and eradication methods for <i>H. pylori</i>. This review aims to highlight what has already been established regarding <i>H. pylori</i>’s epidemiology, pathophysiology, detection, and treatment as well as the most current and novel research involving detection and treatment of <i>H. pylori</i>.https://www.mdpi.com/2079-9721/10/3/57<i>Helicobacter pylori</i>carcinogenesisgastric cancertherapeutic advancementsnovel therapies |
| spellingShingle | Patrick Joseph Tempera Mark Michael Omar Tageldin Stephen Hasak Gastric Cancer Due to Chronic <i>H. pylori</i> Infection: What We Know and Where We Are Going Diseases <i>Helicobacter pylori</i> carcinogenesis gastric cancer therapeutic advancements novel therapies |
| title | Gastric Cancer Due to Chronic <i>H. pylori</i> Infection: What We Know and Where We Are Going |
| title_full | Gastric Cancer Due to Chronic <i>H. pylori</i> Infection: What We Know and Where We Are Going |
| title_fullStr | Gastric Cancer Due to Chronic <i>H. pylori</i> Infection: What We Know and Where We Are Going |
| title_full_unstemmed | Gastric Cancer Due to Chronic <i>H. pylori</i> Infection: What We Know and Where We Are Going |
| title_short | Gastric Cancer Due to Chronic <i>H. pylori</i> Infection: What We Know and Where We Are Going |
| title_sort | gastric cancer due to chronic i h pylori i infection what we know and where we are going |
| topic | <i>Helicobacter pylori</i> carcinogenesis gastric cancer therapeutic advancements novel therapies |
| url | https://www.mdpi.com/2079-9721/10/3/57 |
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