Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis

A 56-year-old woman presented with multiple blisters on the rim of painful erythematous annular lesions over the trunk and four extremities, accompanied with fever and arthralgia on both ankles and feet. Laboratory studies showed neutrophilia and elevated C-reactive protein level. Skin biopsy reveal...

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Main Authors: Shiang-Yu Yang, Chih-Hung Lin, Chung-Hsing Chang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2017-09-01
Series:Dermatologica Sinica
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1027811717300575
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author Shiang-Yu Yang
Chih-Hung Lin
Chung-Hsing Chang
author_facet Shiang-Yu Yang
Chih-Hung Lin
Chung-Hsing Chang
author_sort Shiang-Yu Yang
collection DOAJ
description A 56-year-old woman presented with multiple blisters on the rim of painful erythematous annular lesions over the trunk and four extremities, accompanied with fever and arthralgia on both ankles and feet. Laboratory studies showed neutrophilia and elevated C-reactive protein level. Skin biopsy revealed exuberant edema of the papillary dermis, extensive neutrophil infiltration, and hemophagocytosis within the dermis. Her symptoms and skin lesions resolved 3 days after initiation of systemic corticosteroids. To the best of our knowledge, this is the first case report of cutaneous hemophagocytosis without additional symptoms of hemophagocytic syndrome in patients with Sweet's syndrome.
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spelling doaj.art-a98c6272ea9640e990861a48b3cfb8dd2022-12-22T00:04:19ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172017-09-0135314815110.1016/j.dsi.2017.02.008Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosisShiang-Yu Yang0Chih-Hung Lin1Chung-Hsing Chang2Department of Dermatology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, TaiwanDepartment of Pathology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, TaiwanDepartment of Dermatology, School of Medicine, College of Medicine, China Medical University, Taichung, TaiwanA 56-year-old woman presented with multiple blisters on the rim of painful erythematous annular lesions over the trunk and four extremities, accompanied with fever and arthralgia on both ankles and feet. Laboratory studies showed neutrophilia and elevated C-reactive protein level. Skin biopsy revealed exuberant edema of the papillary dermis, extensive neutrophil infiltration, and hemophagocytosis within the dermis. Her symptoms and skin lesions resolved 3 days after initiation of systemic corticosteroids. To the best of our knowledge, this is the first case report of cutaneous hemophagocytosis without additional symptoms of hemophagocytic syndrome in patients with Sweet's syndrome.http://www.sciencedirect.com/science/article/pii/S1027811717300575autoinflammatory diseasesblistering diseasefigurate erythemahemophagocytosisSweet's syndrome
spellingShingle Shiang-Yu Yang
Chih-Hung Lin
Chung-Hsing Chang
Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis
Dermatologica Sinica
autoinflammatory diseases
blistering disease
figurate erythema
hemophagocytosis
Sweet's syndrome
title Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis
title_full Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis
title_fullStr Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis
title_full_unstemmed Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis
title_short Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis
title_sort bullous sweet s syndrome with figurate erythema and cutaneous hemophagocytosis
topic autoinflammatory diseases
blistering disease
figurate erythema
hemophagocytosis
Sweet's syndrome
url http://www.sciencedirect.com/science/article/pii/S1027811717300575
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AT chihhunglin bulloussweetssyndromewithfigurateerythemaandcutaneoushemophagocytosis
AT chunghsingchang bulloussweetssyndromewithfigurateerythemaandcutaneoushemophagocytosis