Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis
A 56-year-old woman presented with multiple blisters on the rim of painful erythematous annular lesions over the trunk and four extremities, accompanied with fever and arthralgia on both ankles and feet. Laboratory studies showed neutrophilia and elevated C-reactive protein level. Skin biopsy reveal...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2017-09-01
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Series: | Dermatologica Sinica |
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Online Access: | http://www.sciencedirect.com/science/article/pii/S1027811717300575 |
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author | Shiang-Yu Yang Chih-Hung Lin Chung-Hsing Chang |
author_facet | Shiang-Yu Yang Chih-Hung Lin Chung-Hsing Chang |
author_sort | Shiang-Yu Yang |
collection | DOAJ |
description | A 56-year-old woman presented with multiple blisters on the rim of painful erythematous annular lesions over the trunk and four extremities, accompanied with fever and arthralgia on both ankles and feet. Laboratory studies showed neutrophilia and elevated C-reactive protein level. Skin biopsy revealed exuberant edema of the papillary dermis, extensive neutrophil infiltration, and hemophagocytosis within the dermis. Her symptoms and skin lesions resolved 3 days after initiation of systemic corticosteroids. To the best of our knowledge, this is the first case report of cutaneous hemophagocytosis without additional symptoms of hemophagocytic syndrome in patients with Sweet's syndrome. |
first_indexed | 2024-12-13T01:17:13Z |
format | Article |
id | doaj.art-a98c6272ea9640e990861a48b3cfb8dd |
institution | Directory Open Access Journal |
issn | 1027-8117 |
language | English |
last_indexed | 2024-12-13T01:17:13Z |
publishDate | 2017-09-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Dermatologica Sinica |
spelling | doaj.art-a98c6272ea9640e990861a48b3cfb8dd2022-12-22T00:04:19ZengWolters Kluwer Medknow PublicationsDermatologica Sinica1027-81172017-09-0135314815110.1016/j.dsi.2017.02.008Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosisShiang-Yu Yang0Chih-Hung Lin1Chung-Hsing Chang2Department of Dermatology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, TaiwanDepartment of Pathology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, TaiwanDepartment of Dermatology, School of Medicine, College of Medicine, China Medical University, Taichung, TaiwanA 56-year-old woman presented with multiple blisters on the rim of painful erythematous annular lesions over the trunk and four extremities, accompanied with fever and arthralgia on both ankles and feet. Laboratory studies showed neutrophilia and elevated C-reactive protein level. Skin biopsy revealed exuberant edema of the papillary dermis, extensive neutrophil infiltration, and hemophagocytosis within the dermis. Her symptoms and skin lesions resolved 3 days after initiation of systemic corticosteroids. To the best of our knowledge, this is the first case report of cutaneous hemophagocytosis without additional symptoms of hemophagocytic syndrome in patients with Sweet's syndrome.http://www.sciencedirect.com/science/article/pii/S1027811717300575autoinflammatory diseasesblistering diseasefigurate erythemahemophagocytosisSweet's syndrome |
spellingShingle | Shiang-Yu Yang Chih-Hung Lin Chung-Hsing Chang Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis Dermatologica Sinica autoinflammatory diseases blistering disease figurate erythema hemophagocytosis Sweet's syndrome |
title | Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis |
title_full | Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis |
title_fullStr | Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis |
title_full_unstemmed | Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis |
title_short | Bullous Sweet's syndrome with figurate erythema and cutaneous hemophagocytosis |
title_sort | bullous sweet s syndrome with figurate erythema and cutaneous hemophagocytosis |
topic | autoinflammatory diseases blistering disease figurate erythema hemophagocytosis Sweet's syndrome |
url | http://www.sciencedirect.com/science/article/pii/S1027811717300575 |
work_keys_str_mv | AT shiangyuyang bulloussweetssyndromewithfigurateerythemaandcutaneoushemophagocytosis AT chihhunglin bulloussweetssyndromewithfigurateerythemaandcutaneoushemophagocytosis AT chunghsingchang bulloussweetssyndromewithfigurateerythemaandcutaneoushemophagocytosis |