Association between ambient temperature and semen quality among sperm donation volunteers in South China
Background: Potential adverse effects of non-optimum temperatures on human semen quality have drawn much concern worldwide; however, the exposure–response relationship remains less understood. Objectives: To quantitatively assess the association between exposure to ambient temperature and semen qual...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-03-01
|
| Series: | Environment International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S016041202300082X |
| _version_ | 1827987873528283136 |
|---|---|
| author | Xinzong Zhang Zhaoyu Fan Qiling Wang Xinyi Deng Ruijun Xu Yingxin Li Tingting Liu Rui Wang Chunxiang Shi Suli Huang Ziquan Lv Gongbo Chen Yong-Gang Duan Yuewei Liu |
| author_facet | Xinzong Zhang Zhaoyu Fan Qiling Wang Xinyi Deng Ruijun Xu Yingxin Li Tingting Liu Rui Wang Chunxiang Shi Suli Huang Ziquan Lv Gongbo Chen Yong-Gang Duan Yuewei Liu |
| author_sort | Xinzong Zhang |
| collection | DOAJ |
| description | Background: Potential adverse effects of non-optimum temperatures on human semen quality have drawn much concern worldwide; however, the exposure–response relationship remains less understood. Objectives: To quantitatively assess the association between exposure to ambient temperature and semen quality in South China, and to identify potential critical exposure windows. Methods: We conducted a longitudinal study to investigate 11,050 volunteers who lived in Guangdong province, China and intended to donate sperm in the Guangdong provincial human sperm bank during 2016–2021. Exposure to ambient temperature during 0–90 days before semen collection was assessed by extracting daily temperatures from a validated grid dataset at each subject’s residential address. Linear mixed models and linear regression models were used to perform exposure–response analyses. Results: During the study period, the 11,050 subjects underwent 44,564 semen analyses. Each 5 °C increase of lag 0–90 day exposure to ambient temperature was approximately linearly associated with a 3.11 (95 % confidence interval [CI]: 2.08, 4.14) × 106/ml, 9.31 (4.83, 13.80) × 106, 1.27 % (0.91 %, 1.62 %), 8.20 (5.33, 11.08) × 106, 1.37 % (1.01 %, 1.74 %), 8.29 (5.52, 11.06) × 106, 0.67 % (0.28 %, 1.05 %), and 4.50 (2.20, 6.80) × 106 reduction in sperm concentration, total sperm number, total motility, total motile sperm number, progressive motility, total progressive sperm number, normal forms, and total normal form sperm number, respectively (all p < 0.001), which was not significantly modified by age (all p for effect modification > 0.05). We identified a critical exposure period of 10–14 days before semen collection for sperm motility, and 70–90 days before semen collection for sperm count and morphology. Conclusions: Our study provides consistent evidence that higher ambient temperature was significantly associated with a reduction in semen quality in South China. The findings highlight the needs to reduce high temperature exposures during 3 months before ejaculation to maintain better semen quality. |
| first_indexed | 2024-04-09T23:54:55Z |
| format | Article |
| id | doaj.art-a993149b743c46fe824f6ee15740a0bc |
| institution | Directory Open Access Journal |
| issn | 0160-4120 |
| language | English |
| last_indexed | 2024-04-09T23:54:55Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj.art-a993149b743c46fe824f6ee15740a0bc2023-03-17T04:32:15ZengElsevierEnvironment International0160-41202023-03-01173107809Association between ambient temperature and semen quality among sperm donation volunteers in South ChinaXinzong Zhang0Zhaoyu Fan1Qiling Wang2Xinyi Deng3Ruijun Xu4Yingxin Li5Tingting Liu6Rui Wang7Chunxiang Shi8Suli Huang9Ziquan Lv10Gongbo Chen11Yong-Gang Duan12Yuewei Liu13NHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute, Guangdong Provincial Fertility Hospital, Guangzhou, Guangdong 510600, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaNHC Key Laboratory of Male Reproduction and Genetics, Guangdong Provincial Reproductive Science Institute, Guangdong Provincial Fertility Hospital, Guangzhou, Guangdong 510600, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaLuohu District Chronic Disease Hospital, Shenzhen, Guangdong 518020, ChinaMeteorological Data Laboratory, National Meteorological Information Center, Beijing 100081, ChinaDepartment of Environment and Health, Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong 518055, ChinaCentral Laboratory of Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong 518055, ChinaDepartment of Occupational and Environmental Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, ChinaShenzhen Key Laboratory of Fertility Regulation, Centre of Assisted Reproduction and Embryology, The University of Hong Kong - Shenzhen Hospital, Shenzhen, Guangdong 518053, ChinaDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, China; Corresponding author at: Department of Epidemiology, School of Public Health, Sun Yat-sen University. 74 Zhongshan Second Road, Guangzhou, Guangdong 510080, China.Background: Potential adverse effects of non-optimum temperatures on human semen quality have drawn much concern worldwide; however, the exposure–response relationship remains less understood. Objectives: To quantitatively assess the association between exposure to ambient temperature and semen quality in South China, and to identify potential critical exposure windows. Methods: We conducted a longitudinal study to investigate 11,050 volunteers who lived in Guangdong province, China and intended to donate sperm in the Guangdong provincial human sperm bank during 2016–2021. Exposure to ambient temperature during 0–90 days before semen collection was assessed by extracting daily temperatures from a validated grid dataset at each subject’s residential address. Linear mixed models and linear regression models were used to perform exposure–response analyses. Results: During the study period, the 11,050 subjects underwent 44,564 semen analyses. Each 5 °C increase of lag 0–90 day exposure to ambient temperature was approximately linearly associated with a 3.11 (95 % confidence interval [CI]: 2.08, 4.14) × 106/ml, 9.31 (4.83, 13.80) × 106, 1.27 % (0.91 %, 1.62 %), 8.20 (5.33, 11.08) × 106, 1.37 % (1.01 %, 1.74 %), 8.29 (5.52, 11.06) × 106, 0.67 % (0.28 %, 1.05 %), and 4.50 (2.20, 6.80) × 106 reduction in sperm concentration, total sperm number, total motility, total motile sperm number, progressive motility, total progressive sperm number, normal forms, and total normal form sperm number, respectively (all p < 0.001), which was not significantly modified by age (all p for effect modification > 0.05). We identified a critical exposure period of 10–14 days before semen collection for sperm motility, and 70–90 days before semen collection for sperm count and morphology. Conclusions: Our study provides consistent evidence that higher ambient temperature was significantly associated with a reduction in semen quality in South China. The findings highlight the needs to reduce high temperature exposures during 3 months before ejaculation to maintain better semen quality.http://www.sciencedirect.com/science/article/pii/S016041202300082XAmbient temperatureSemen qualitySperm countSperm motilitySperm morphologySperm donation volunteer |
| spellingShingle | Xinzong Zhang Zhaoyu Fan Qiling Wang Xinyi Deng Ruijun Xu Yingxin Li Tingting Liu Rui Wang Chunxiang Shi Suli Huang Ziquan Lv Gongbo Chen Yong-Gang Duan Yuewei Liu Association between ambient temperature and semen quality among sperm donation volunteers in South China Environment International Ambient temperature Semen quality Sperm count Sperm motility Sperm morphology Sperm donation volunteer |
| title | Association between ambient temperature and semen quality among sperm donation volunteers in South China |
| title_full | Association between ambient temperature and semen quality among sperm donation volunteers in South China |
| title_fullStr | Association between ambient temperature and semen quality among sperm donation volunteers in South China |
| title_full_unstemmed | Association between ambient temperature and semen quality among sperm donation volunteers in South China |
| title_short | Association between ambient temperature and semen quality among sperm donation volunteers in South China |
| title_sort | association between ambient temperature and semen quality among sperm donation volunteers in south china |
| topic | Ambient temperature Semen quality Sperm count Sperm motility Sperm morphology Sperm donation volunteer |
| url | http://www.sciencedirect.com/science/article/pii/S016041202300082X |
| work_keys_str_mv | AT xinzongzhang associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT zhaoyufan associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT qilingwang associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT xinyideng associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT ruijunxu associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT yingxinli associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT tingtingliu associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT ruiwang associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT chunxiangshi associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT sulihuang associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT ziquanlv associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT gongbochen associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT yonggangduan associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina AT yueweiliu associationbetweenambienttemperatureandsemenqualityamongspermdonationvolunteersinsouthchina |