Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications
This review describes the most common methods for recovery of chitin from marine organisms. In depth, both enzymatic and chemical treatments for the step of deproteinization are compared, as well as different conditions for demineralization. The conditions of chitosan preparation are also discussed,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-03-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1660-3397/13/3/1133 |
| _version_ | 1828233470511415296 |
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| author | Islem Younes Marguerite Rinaudo |
| author_facet | Islem Younes Marguerite Rinaudo |
| author_sort | Islem Younes |
| collection | DOAJ |
| description | This review describes the most common methods for recovery of chitin from marine organisms. In depth, both enzymatic and chemical treatments for the step of deproteinization are compared, as well as different conditions for demineralization. The conditions of chitosan preparation are also discussed, since they significantly impact the synthesis of chitosan with varying degree of acetylation (DA) and molecular weight (MW). In addition, the main characterization techniques applied for chitin and chitosan are recalled, pointing out the role of their solubility in relation with the chemical structure (mainly the acetyl group distribution along the backbone). Biological activities are also presented, such as: antibacterial, antifungal, antitumor and antioxidant. Interestingly, the relationship between chemical structure and biological activity is demonstrated for chitosan molecules with different DA and MW and homogeneous distribution of acetyl groups for the first time. In the end, several selected pharmaceutical and biomedical applications are presented, in which chitin and chitosan are recognized as new biomaterials taking advantage of their biocompatibility and biodegradability. |
| first_indexed | 2024-04-12T19:39:54Z |
| format | Article |
| id | doaj.art-a993fd80a66b41c5bd393aaf2cf65d98 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-04-12T19:39:54Z |
| publishDate | 2015-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-a993fd80a66b41c5bd393aaf2cf65d982022-12-22T03:19:07ZengMDPI AGMarine Drugs1660-33972015-03-011331133117410.3390/md13031133md13031133Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and ApplicationsIslem Younes0Marguerite Rinaudo1Laboratory of Enzyme Engineering and Microbiology, University of Sfax, National School of Engineering, PO Box 1173-3038, Sfax, TunisiaBiomaterials Applications, 6 rue Lesdiguières, Grenoble 38000, FranceThis review describes the most common methods for recovery of chitin from marine organisms. In depth, both enzymatic and chemical treatments for the step of deproteinization are compared, as well as different conditions for demineralization. The conditions of chitosan preparation are also discussed, since they significantly impact the synthesis of chitosan with varying degree of acetylation (DA) and molecular weight (MW). In addition, the main characterization techniques applied for chitin and chitosan are recalled, pointing out the role of their solubility in relation with the chemical structure (mainly the acetyl group distribution along the backbone). Biological activities are also presented, such as: antibacterial, antifungal, antitumor and antioxidant. Interestingly, the relationship between chemical structure and biological activity is demonstrated for chitosan molecules with different DA and MW and homogeneous distribution of acetyl groups for the first time. In the end, several selected pharmaceutical and biomedical applications are presented, in which chitin and chitosan are recognized as new biomaterials taking advantage of their biocompatibility and biodegradability.http://www.mdpi.com/1660-3397/13/3/1133chitinchitosanchemical and enzymatic deproteinizationdemineralizationcharacterizationdeacetylationbiological activitiesbiomedical applications |
| spellingShingle | Islem Younes Marguerite Rinaudo Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications Marine Drugs chitin chitosan chemical and enzymatic deproteinization demineralization characterization deacetylation biological activities biomedical applications |
| title | Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications |
| title_full | Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications |
| title_fullStr | Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications |
| title_full_unstemmed | Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications |
| title_short | Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications |
| title_sort | chitin and chitosan preparation from marine sources structure properties and applications |
| topic | chitin chitosan chemical and enzymatic deproteinization demineralization characterization deacetylation biological activities biomedical applications |
| url | http://www.mdpi.com/1660-3397/13/3/1133 |
| work_keys_str_mv | AT islemyounes chitinandchitosanpreparationfrommarinesourcesstructurepropertiesandapplications AT margueriterinaudo chitinandchitosanpreparationfrommarinesourcesstructurepropertiesandapplications |