Combination of NK Cells and Cetuximab to Enhance Anti-Tumor Responses in RAS Mutant Metastatic Colorectal Cancer.
The ability of Natural Killer (NK) cells to kill tumor targets has been extensively studied in various hematological malignancies. However, NK cell therapy directed against solid tumors is still in early development. Epidermal Growth Factor Receptor (EGFR) targeted therapies using monoclonal antibod...
Main Authors: | John Pradeep Veluchamy, Jan Spanholtz, Marleen Tordoir, Victor L Thijssen, Daniëlle A M Heideman, Henk M W Verheul, Tanja D de Gruijl, Hans J van der Vliet |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4912059?pdf=render |
Similar Items
-
Allogeneic NK cells induce monocyte-to-dendritic cell conversion, control tumor growth, and trigger a pro-inflammatory shift in patient-derived cultures of primary and metastatic colorectal cancer
by: Tanja D de Gruijl, et al.
Published: (2023-12-01) -
634 Production and testing of a novel bispecific nanobody construct targeting NK cells and EGFR expressing malignancies
by: Henk Verheul, et al.
Published: (2020-11-01) -
The Rise of Allogeneic Natural Killer Cells As a Platform for Cancer Immunotherapy: Recent Innovations and Future Developments
by: John P. Veluchamy, et al.
Published: (2017-05-01) -
RAS and BRAF mutations in cell‐free DNA are predictive for outcome of cetuximab monotherapy in patients with tissue‐tested RAS wild‐type advanced colorectal cancer
by: Erik J. vanHelden, et al.
Published: (2019-11-01) -
Primary tumor location predicts poor clinical outcome with cetuximab in RAS wild-type metastatic colorectal cancer
by: Dalyong Kim, et al.
Published: (2017-11-01)