L1 cell adhesion molecule as a potential therapeutic target in murine models of endometriosis using a monoclonal antibody approach.

L1 cell adhesion molecule as a potential therapeutic target in murine models of endometriosis using a monoclonal antibody approach.

BACKGROUND/AIMS: The neural cell adhesion molecule L1CAM is a transmembrane glycoprotein abnormally expressed in tumors and previously associated with cell proliferation, adhesion and invasion, as well as neurite outgrowth in endometriosis. Being an attractive target molecule for antibody-based ther...

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Bibliographic Details
Main Authors: Cássia G T Silveira, Dominique Finas, Peter Hunold, Frank Köster, Katharina Stroschein, Geraldine O Canny, Gerhard Moldenhauer, Peter Altevogt, Achim Rody, Daniela Hornung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3853202?pdf=render

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