Tubulointerstitial nephritis and uveitis syndrome: An atypical case
Tubulointerstitial nephritis and uveitis syndrome is an uncommon clinical entity. Usually, renal involvement is moderate, and uveitis is acute, bilateral, anterior, and nongranulomatous (revised). We present the case of a 55-year-old female patient who went to the emergency department with complaint...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2020-01-01
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| Series: | The Pan-American Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.thepajo.org/article.asp?issn=2666-4909;year=2020;volume=2;issue=1;spage=39;epage=39;aulast=Diniz |
| _version_ | 1818832871799914496 |
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| author | Silvia Cunha Diniz Pedro Prata Gomes Inês Figueiredo Matias Bruno Sousa Pina Pedro Pereira Neves Mário Correa Ornelas |
| author_facet | Silvia Cunha Diniz Pedro Prata Gomes Inês Figueiredo Matias Bruno Sousa Pina Pedro Pereira Neves Mário Correa Ornelas |
| author_sort | Silvia Cunha Diniz |
| collection | DOAJ |
| description | Tubulointerstitial nephritis and uveitis syndrome is an uncommon clinical entity. Usually, renal involvement is moderate, and uveitis is acute, bilateral, anterior, and nongranulomatous (revised). We present the case of a 55-year-old female patient who went to the emergency department with complaints of asthenia, myalgia, and paresthesia. One week later, she complained of photophobia and was diagnosed with bilateral nongranulomatous acute anterior uveitis. The next day, due to hypotension and acute kidney injury, the patient was hospitalized. Renal biopsy showed tubulointerstitial nephritis. The patient was started on oral prednisolone, achieving uveitis resolution and renal function stability. After slow corticoid reduction, the patient presented uveitis recurrence complicated with bilateral optic disc (revised) edema and cystoid macular edema (CME) in the left eye. After oral prednisolone reduction, the patient suffered another relapse with CME worsening. We decided to initiate methotrexate 7.5 mg/week, achieving ocular and renal function stability. |
| first_indexed | 2024-12-19T02:09:55Z |
| format | Article |
| id | doaj.art-a99bc620bbee40a7a44cf2815861289c |
| institution | Directory Open Access Journal |
| issn | 2666-4909 2666-4909 |
| language | English |
| last_indexed | 2024-12-19T02:09:55Z |
| publishDate | 2020-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | The Pan-American Journal of Ophthalmology |
| spelling | doaj.art-a99bc620bbee40a7a44cf2815861289c2022-12-21T20:40:50ZengWolters Kluwer Medknow PublicationsThe Pan-American Journal of Ophthalmology2666-49092666-49092020-01-0121393910.4103/pajo.pajo_51_20Tubulointerstitial nephritis and uveitis syndrome: An atypical caseSilvia Cunha DinizPedro Prata GomesInês Figueiredo MatiasBruno Sousa PinaPedro Pereira NevesMário Correa OrnelasTubulointerstitial nephritis and uveitis syndrome is an uncommon clinical entity. Usually, renal involvement is moderate, and uveitis is acute, bilateral, anterior, and nongranulomatous (revised). We present the case of a 55-year-old female patient who went to the emergency department with complaints of asthenia, myalgia, and paresthesia. One week later, she complained of photophobia and was diagnosed with bilateral nongranulomatous acute anterior uveitis. The next day, due to hypotension and acute kidney injury, the patient was hospitalized. Renal biopsy showed tubulointerstitial nephritis. The patient was started on oral prednisolone, achieving uveitis resolution and renal function stability. After slow corticoid reduction, the patient presented uveitis recurrence complicated with bilateral optic disc (revised) edema and cystoid macular edema (CME) in the left eye. After oral prednisolone reduction, the patient suffered another relapse with CME worsening. We decided to initiate methotrexate 7.5 mg/week, achieving ocular and renal function stability.http://www.thepajo.org/article.asp?issn=2666-4909;year=2020;volume=2;issue=1;spage=39;epage=39;aulast=Dinizacute kidney injurycorticoidtubulointerstitial nephritisuveitis |
| spellingShingle | Silvia Cunha Diniz Pedro Prata Gomes Inês Figueiredo Matias Bruno Sousa Pina Pedro Pereira Neves Mário Correa Ornelas Tubulointerstitial nephritis and uveitis syndrome: An atypical case The Pan-American Journal of Ophthalmology acute kidney injury corticoid tubulointerstitial nephritis uveitis |
| title | Tubulointerstitial nephritis and uveitis syndrome: An atypical case |
| title_full | Tubulointerstitial nephritis and uveitis syndrome: An atypical case |
| title_fullStr | Tubulointerstitial nephritis and uveitis syndrome: An atypical case |
| title_full_unstemmed | Tubulointerstitial nephritis and uveitis syndrome: An atypical case |
| title_short | Tubulointerstitial nephritis and uveitis syndrome: An atypical case |
| title_sort | tubulointerstitial nephritis and uveitis syndrome an atypical case |
| topic | acute kidney injury corticoid tubulointerstitial nephritis uveitis |
| url | http://www.thepajo.org/article.asp?issn=2666-4909;year=2020;volume=2;issue=1;spage=39;epage=39;aulast=Diniz |
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