Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department
Introduction: New evidence suggests that emergency department (ED)-based infectious diseases screening programs have utility. We aimed to compare clinic-based and ED-based hepatitis C virus (HCV) screening programs within a single health system, to identify key differences in HCV antibody (Ab) posit...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
eScholarship Publishing, University of California
2022-03-01
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| Series: | Western Journal of Emergency Medicine |
| Online Access: | https://escholarship.org/uc/item/9r38c53x |
| _version_ | 1811258244700569600 |
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| author | Rebecca Hluhanich James S. Ford Devin Bruce Tasleem Chechi Stephanie Voong Souvik Sarkar Patricia Poole Nam Tran Larissa May |
| author_facet | Rebecca Hluhanich James S. Ford Devin Bruce Tasleem Chechi Stephanie Voong Souvik Sarkar Patricia Poole Nam Tran Larissa May |
| author_sort | Rebecca Hluhanich |
| collection | DOAJ |
| description | Introduction: New evidence suggests that emergency department (ED)-based infectious diseases screening programs have utility. We aimed to compare clinic-based and ED-based hepatitis C virus (HCV) screening programs within a single health system, to identify key differences in HCV antibody (Ab) positivity and chronic HCV, as well as population demographics. Methods: In the clinic-based program, adults in the birth cohort (born 1945–1965) were screened for HCV. In the ED-based program, non-targeted HCV screening of all adults was conducted. We included patients screened between June 2019–June 2020. Patients were screened for anti-HCV Ab, and positive results were followed by HCV viral load (VL) testing. Our primary outcomes were seroprevalence of HCV Ab and HCV VL. Results: There were 1,296 and 12,778 patients screened for HCV in the clinics and the ED, respectively. In the clinic setting, 13 patients (1%) screened positive for HCV Ab and nine (69%) completed VL testing, which was positive in one patient (11%). In the ED, 1,053 patients (8%) screened positive for HCV Ab and 847 (80%) underwent reflex VL testing, which was positive in 381 patients (45%). In an ED birth cohort sub-analysis, Hepatitis C virus Ab seroprevalence was 15% (675/4521). Conclusion: In this study of patients in a single healthcare system, ED-based HCV screening was higher yield than clinic-based screening. |
| first_indexed | 2024-04-12T18:11:21Z |
| format | Article |
| id | doaj.art-a99d46779d964bd784397c39ec81d75e |
| institution | Directory Open Access Journal |
| issn | 1936-9018 |
| language | English |
| last_indexed | 2024-04-12T18:11:21Z |
| publishDate | 2022-03-01 |
| publisher | eScholarship Publishing, University of California |
| record_format | Article |
| series | Western Journal of Emergency Medicine |
| spelling | doaj.art-a99d46779d964bd784397c39ec81d75e2022-12-22T03:21:50ZengeScholarship Publishing, University of CaliforniaWestern Journal of Emergency Medicine1936-90182022-03-0123310.5811/westjem.2021.11.53870wjem-23-312Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency DepartmentRebecca Hluhanich0James S. Ford1Devin Bruce2Tasleem Chechi3Stephanie Voong4Souvik Sarkar5Patricia Poole6Nam Tran7Larissa May8UC Davis Health, Hepatology and Infectious Diseases Clinical Pharmacy, Sacramento, CaliforniaUC Davis Health, Department of Emergency Medicine, Sacramento, CaliforniaUC Davis Health, Department of Emergency Medicine, Sacramento, CaliforniaUC Davis Health, Department of Emergency Medicine, Sacramento, CaliforniaUC Davis Health, Department of Emergency Medicine, Sacramento, CaliforniaUC Davis Health, Department of Internal Medicine, Division of Gastroenterology, Sacramento, CaliforniaUC Davis Health, Department of Pharmacy, Sacramento, CaliforniaUC Davis Health, Department of Pathology and Laboratory Medicine, Sacramento, CaliforniaUC Davis Health, Department of Emergency Medicine, Sacramento, CaliforniaIntroduction: New evidence suggests that emergency department (ED)-based infectious diseases screening programs have utility. We aimed to compare clinic-based and ED-based hepatitis C virus (HCV) screening programs within a single health system, to identify key differences in HCV antibody (Ab) positivity and chronic HCV, as well as population demographics. Methods: In the clinic-based program, adults in the birth cohort (born 1945–1965) were screened for HCV. In the ED-based program, non-targeted HCV screening of all adults was conducted. We included patients screened between June 2019–June 2020. Patients were screened for anti-HCV Ab, and positive results were followed by HCV viral load (VL) testing. Our primary outcomes were seroprevalence of HCV Ab and HCV VL. Results: There were 1,296 and 12,778 patients screened for HCV in the clinics and the ED, respectively. In the clinic setting, 13 patients (1%) screened positive for HCV Ab and nine (69%) completed VL testing, which was positive in one patient (11%). In the ED, 1,053 patients (8%) screened positive for HCV Ab and 847 (80%) underwent reflex VL testing, which was positive in 381 patients (45%). In an ED birth cohort sub-analysis, Hepatitis C virus Ab seroprevalence was 15% (675/4521). Conclusion: In this study of patients in a single healthcare system, ED-based HCV screening was higher yield than clinic-based screening.https://escholarship.org/uc/item/9r38c53x |
| spellingShingle | Rebecca Hluhanich James S. Ford Devin Bruce Tasleem Chechi Stephanie Voong Souvik Sarkar Patricia Poole Nam Tran Larissa May Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department Western Journal of Emergency Medicine |
| title | Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department |
| title_full | Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department |
| title_fullStr | Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department |
| title_full_unstemmed | Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department |
| title_short | Comparing Hepatitis C Virus Screening in Clinics Versus the Emergency Department |
| title_sort | comparing hepatitis c virus screening in clinics versus the emergency department |
| url | https://escholarship.org/uc/item/9r38c53x |
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