New Bis(dithiocarbamate) Ligand for Complex Formation; Synthesis, Spectral Analysis and Bacterial Activity
A range of macrocyclic dinuclear metal (II) dithiocarbamate-based complexes are reported. The preparation of complexes was accomplished from either mixing of the prepared ligand with a metal ion or through a template one-pot reaction. The preparation of the bisamine precursor was achieved through s...
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| Format: | Article |
| Language: | English |
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University of Baghdad
2017-06-01
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| Series: | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| Subjects: | |
| Online Access: | https://jih.uobaghdad.edu.iq/index.php/j/article/view/1061 |
| _version_ | 1811309443613196288 |
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| author | Enaam I. Yousif Hasan A. Hasan |
| author_facet | Enaam I. Yousif Hasan A. Hasan |
| author_sort | Enaam I. Yousif |
| collection | DOAJ |
| description |
A range of macrocyclic dinuclear metal (II) dithiocarbamate-based complexes are reported. The preparation of complexes was accomplished from either mixing of the prepared ligand with a metal ion or through a template one-pot reaction. The preparation of the bisamine precursor was achieved through several synthetic steps. The free ligand; potassium 2,2'-(biphenyl-4,4'-diylbis(azanediyl))bis(1-chloro-2-oxoethane-2,1diyl)bis(cyclohexylcarbamodithioate) (L) was yielded from the addition of CS2 to a bis-amine precursor in KOH medium.A variety of analytical and physical methods were implemented to characterise ligand and its complexes. The analyses were based on spectroscopic techniques (FTIR, UV-Vis, mass spectroscopy and 1H, 13C-NMR spectroscopy), melting points, elemental analysis, thermal properties, magnetic susceptibility and conductance. The analytical and physical techniques confirmed the formation of macrocyclic complexes of the general formulae [M(L)]2 (M= MnII, CoII, NiII, CuII, ZnII and CdII). The proposed structure around MnII, CoII, ZnII and CdII is a tetrahedral, while NiII and CuII complexes adopt square planar geometries. The prepared compounds were screened against four bacterial species (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus stubtilis). The anti-bacterial test indicated that the complexes are more active against these bacterial strains, compared with the free ligand.
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| first_indexed | 2024-04-13T09:42:09Z |
| format | Article |
| id | doaj.art-a99e4f571a05479d90869a9970d6498f |
| institution | Directory Open Access Journal |
| issn | 1609-4042 2521-3407 |
| language | English |
| last_indexed | 2024-04-13T09:42:09Z |
| publishDate | 2017-06-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| spelling | doaj.art-a99e4f571a05479d90869a9970d6498f2022-12-22T02:51:53ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072017-06-01301New Bis(dithiocarbamate) Ligand for Complex Formation; Synthesis, Spectral Analysis and Bacterial ActivityEnaam I. YousifHasan A. Hasan A range of macrocyclic dinuclear metal (II) dithiocarbamate-based complexes are reported. The preparation of complexes was accomplished from either mixing of the prepared ligand with a metal ion or through a template one-pot reaction. The preparation of the bisamine precursor was achieved through several synthetic steps. The free ligand; potassium 2,2'-(biphenyl-4,4'-diylbis(azanediyl))bis(1-chloro-2-oxoethane-2,1diyl)bis(cyclohexylcarbamodithioate) (L) was yielded from the addition of CS2 to a bis-amine precursor in KOH medium.A variety of analytical and physical methods were implemented to characterise ligand and its complexes. The analyses were based on spectroscopic techniques (FTIR, UV-Vis, mass spectroscopy and 1H, 13C-NMR spectroscopy), melting points, elemental analysis, thermal properties, magnetic susceptibility and conductance. The analytical and physical techniques confirmed the formation of macrocyclic complexes of the general formulae [M(L)]2 (M= MnII, CoII, NiII, CuII, ZnII and CdII). The proposed structure around MnII, CoII, ZnII and CdII is a tetrahedral, while NiII and CuII complexes adopt square planar geometries. The prepared compounds were screened against four bacterial species (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus stubtilis). The anti-bacterial test indicated that the complexes are more active against these bacterial strains, compared with the free ligand. https://jih.uobaghdad.edu.iq/index.php/j/article/view/1061Bis(dithiocarbamate) ligand; Metal complexes; Spectral studies; Thermal properties; Bacterial activity. |
| spellingShingle | Enaam I. Yousif Hasan A. Hasan New Bis(dithiocarbamate) Ligand for Complex Formation; Synthesis, Spectral Analysis and Bacterial Activity Ibn Al-Haitham Journal for Pure and Applied Sciences Bis(dithiocarbamate) ligand; Metal complexes; Spectral studies; Thermal properties; Bacterial activity. |
| title | New Bis(dithiocarbamate) Ligand for Complex Formation; Synthesis, Spectral Analysis and Bacterial Activity |
| title_full | New Bis(dithiocarbamate) Ligand for Complex Formation; Synthesis, Spectral Analysis and Bacterial Activity |
| title_fullStr | New Bis(dithiocarbamate) Ligand for Complex Formation; Synthesis, Spectral Analysis and Bacterial Activity |
| title_full_unstemmed | New Bis(dithiocarbamate) Ligand for Complex Formation; Synthesis, Spectral Analysis and Bacterial Activity |
| title_short | New Bis(dithiocarbamate) Ligand for Complex Formation; Synthesis, Spectral Analysis and Bacterial Activity |
| title_sort | new bis dithiocarbamate ligand for complex formation synthesis spectral analysis and bacterial activity |
| topic | Bis(dithiocarbamate) ligand; Metal complexes; Spectral studies; Thermal properties; Bacterial activity. |
| url | https://jih.uobaghdad.edu.iq/index.php/j/article/view/1061 |
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