Recommendations for Advancing the Diagnosis and Management of Hereditary Breast and Ovarian Cancer in Brazil
PURPOSE The objective of this review was to address the barriers limiting access to genetic cancer risk assessment and genetic testing for individuals with suspected hereditary breast and ovarian cancer (HBOC) through a review of the diagnosis and management steps of HBOC. METHODS A selected panel o...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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American Society of Clinical Oncology
2020-11-01
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| Series: | JCO Global Oncology |
| Online Access: | https://ascopubs.org/doi/10.1200/JGO.19.00170 |
| _version_ | 1828915724259688448 |
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| author | Maria Isabel Achatz Maira Caleffi Rodrigo Guindalini Renato Moretti Marques Angelica Nogueira-Rodrigues Patricia Ashton-Prolla |
| author_facet | Maria Isabel Achatz Maira Caleffi Rodrigo Guindalini Renato Moretti Marques Angelica Nogueira-Rodrigues Patricia Ashton-Prolla |
| author_sort | Maria Isabel Achatz |
| collection | DOAJ |
| description | PURPOSE The objective of this review was to address the barriers limiting access to genetic cancer risk assessment and genetic testing for individuals with suspected hereditary breast and ovarian cancer (HBOC) through a review of the diagnosis and management steps of HBOC. METHODS A selected panel of Brazilian experts in fields related to HBOC was provided with a series of relevant questions to address before the multiday conference. During this conference, each narrative was discussed and edited by the entire group, through numerous drafts and rounds of discussion, until a consensus was achieved. RESULTS The authors propose specific and realistic recommendations for improving access to early diagnosis, risk management, and cancer care of HBOC specific to Brazil. Moreover, in creating these recommendations, the authors strived to address all the barriers and impediments mentioned in this article. CONCLUSION There is a great need to expand hereditary cancer testing and counseling in Brazil, and changing current policies is essential to accomplishing this goal. Increased knowledge and awareness, together with regulatory actions to increase access to this technology, have the potential to improve patient care and prevention and treatment efforts for patients with cancer across the country. |
| first_indexed | 2024-12-13T20:19:23Z |
| format | Article |
| id | doaj.art-a9a11f3228a54589a1af60abb0fbbeb1 |
| institution | Directory Open Access Journal |
| issn | 2687-8941 |
| language | English |
| last_indexed | 2024-12-13T20:19:23Z |
| publishDate | 2020-11-01 |
| publisher | American Society of Clinical Oncology |
| record_format | Article |
| series | JCO Global Oncology |
| spelling | doaj.art-a9a11f3228a54589a1af60abb0fbbeb12022-12-21T23:32:44ZengAmerican Society of Clinical OncologyJCO Global Oncology2687-89412020-11-01643945210.1200/JGO.19.00170Recommendations for Advancing the Diagnosis and Management of Hereditary Breast and Ovarian Cancer in BrazilMaria Isabel Achatz0Maira Caleffi1Rodrigo Guindalini2Renato Moretti Marques3Angelica Nogueira-Rodrigues4Patricia Ashton-Prolla5Centro de Oncologia, Hospital Sírio-Libanês, São Paulo, BrazilNucleo Mama Porto Alegre and Associação Hospitalar Moinhos de Vento, Porto Alegre, BrazilOncologia D’or, Rede D’or São Luiz, BrazilPrograma da Saúde da Mulher, Hospital Israelita Albert Einstein, São Paulo, BrazilUniversidade Federal de Minas Gerais, Belo Horizonte, BrazilDepartmento de Genética, Universidade Federal do Rio Grande do SulPURPOSE The objective of this review was to address the barriers limiting access to genetic cancer risk assessment and genetic testing for individuals with suspected hereditary breast and ovarian cancer (HBOC) through a review of the diagnosis and management steps of HBOC. METHODS A selected panel of Brazilian experts in fields related to HBOC was provided with a series of relevant questions to address before the multiday conference. During this conference, each narrative was discussed and edited by the entire group, through numerous drafts and rounds of discussion, until a consensus was achieved. RESULTS The authors propose specific and realistic recommendations for improving access to early diagnosis, risk management, and cancer care of HBOC specific to Brazil. Moreover, in creating these recommendations, the authors strived to address all the barriers and impediments mentioned in this article. CONCLUSION There is a great need to expand hereditary cancer testing and counseling in Brazil, and changing current policies is essential to accomplishing this goal. Increased knowledge and awareness, together with regulatory actions to increase access to this technology, have the potential to improve patient care and prevention and treatment efforts for patients with cancer across the country.https://ascopubs.org/doi/10.1200/JGO.19.00170 |
| spellingShingle | Maria Isabel Achatz Maira Caleffi Rodrigo Guindalini Renato Moretti Marques Angelica Nogueira-Rodrigues Patricia Ashton-Prolla Recommendations for Advancing the Diagnosis and Management of Hereditary Breast and Ovarian Cancer in Brazil JCO Global Oncology |
| title | Recommendations for Advancing the Diagnosis and Management of Hereditary Breast and Ovarian Cancer in Brazil |
| title_full | Recommendations for Advancing the Diagnosis and Management of Hereditary Breast and Ovarian Cancer in Brazil |
| title_fullStr | Recommendations for Advancing the Diagnosis and Management of Hereditary Breast and Ovarian Cancer in Brazil |
| title_full_unstemmed | Recommendations for Advancing the Diagnosis and Management of Hereditary Breast and Ovarian Cancer in Brazil |
| title_short | Recommendations for Advancing the Diagnosis and Management of Hereditary Breast and Ovarian Cancer in Brazil |
| title_sort | recommendations for advancing the diagnosis and management of hereditary breast and ovarian cancer in brazil |
| url | https://ascopubs.org/doi/10.1200/JGO.19.00170 |
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