Plasma interleukin-27 (IL-27) levels are not modulated in patients with chronic HIV-1 infection.
IL-27 is an immunomodulatory cytokine with potent anti-HIV properties in PBMCs, CD4+ T cells, macrophages and immature dendritic cells. Previous smaller studies have suggested that HIV-1 infection may alter IL-27 and influence HIV-1 pathogenesis. The aim of this study was to examine the relationship...
Main Authors: | Sanjay Swaminathan, Zonghui Hu, Adam W Rupert, Jeanette M Higgins, Robin L Dewar, Randy Stevens, Qian Chen, Catherine A Rehm, Julia A Metcalf, Michael W Baseler, H Clifford Lane, Tomozumi Imamichi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4045808?pdf=render |
Similar Items
-
Interleukin-15 (IL-15) Strongly Correlates with Increasing HIV-1 Viremia and Markers of Inflammation.
by: Sanjay Swaminathan, et al.
Published: (2016-01-01) -
Editorial: IL-27 in health and disease
by: Tomozumi Imamichi, et al.
Published: (2023-03-01) -
Interleukin-27-induced HIV-resistant dendritic cells suppress reveres transcription following virus entry in an SPTBN1, autophagy, and YB-1 independent manner.
by: Tomozumi Imamichi, et al.
Published: (2023-01-01) -
Interleukin-27-induced HIV-resistant dendritic cells suppress reveres transcription following virus entry in an SPTBN1, autophagy, and YB-1 independent manner
by: Tomozumi Imamichi, et al.
Published: (2023-01-01) -
Interleukin-27 promotes autophagy in human serum-induced primary macrophages via an mTOR- and LC3-independent pathway
by: Sylvain Laverdure, et al.
Published: (2021-07-01)