Jin’s three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial
Abstract Background With an unclear pathomechanism, no confirmed treatment regimen has been established for chronic fatigue syndrome (CFS). Acupuncture is applied as an alternative therapy for CFS. As a kind of acupuncture therapy, Jin’s three-needle acupuncture (JTN) has been applied to treat CFS....
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| Format: | Article |
| Language: | English |
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BMC
2019-03-01
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| Series: | Trials |
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| Online Access: | http://link.springer.com/article/10.1186/s13063-019-3243-5 |
| _version_ | 1818334426307756032 |
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| author | Wenjia Lin Xin-lin Chen Qi Chen Junmao Wen Xinghua Chen |
| author_facet | Wenjia Lin Xin-lin Chen Qi Chen Junmao Wen Xinghua Chen |
| author_sort | Wenjia Lin |
| collection | DOAJ |
| description | Abstract Background With an unclear pathomechanism, no confirmed treatment regimen has been established for chronic fatigue syndrome (CFS). Acupuncture is applied as an alternative therapy for CFS. As a kind of acupuncture therapy, Jin’s three-needle acupuncture (JTN) has been applied to treat CFS. However, few large-sample randomised controlled trials on JTN treatment for CFS have been reported. We designed this study to evaluate the efficacy and safety of JTN treatment for CFS. Method/design This study is a multicentre, single-blind, randomised controlled trial. Patients who meet the inclusion criteria will be recruited and randomly assigned to either the JTN treatment group or the basic acupuncture group. Both interventions will be conducted for five consecutive days per week and last for 2 weeks. The primary outcome is the effective rate based on the 14-item Fatigue Scale (FS-14) score. Other outcome measures include the Fatigue Assessment Scale (FAI), the Depression Status Inventory (DSI), and the Self-rating Anxiety Scale (SAS). Plasma adrenocorticotropic hormone (ACTH), plasma cortisol, and serum levels of IL-2 and IFN-γ will also be measured in this study. Adverse events will be observed and recorded for the safety evaluation. Discussion This study may help to identify the efficacy and safety of JTN acupuncture treatment for CFS. Trial registration Chinese Clinical Trial Registry, ID: ChiCTR-IOR-17011009. Registered on 29 March 2017. |
| first_indexed | 2024-12-13T14:07:20Z |
| format | Article |
| id | doaj.art-a9a38f8aeffe4054abcc4f82edf5c60b |
| institution | Directory Open Access Journal |
| issn | 1745-6215 |
| language | English |
| last_indexed | 2024-12-13T14:07:20Z |
| publishDate | 2019-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Trials |
| spelling | doaj.art-a9a38f8aeffe4054abcc4f82edf5c60b2022-12-21T23:42:34ZengBMCTrials1745-62152019-03-012011910.1186/s13063-019-3243-5Jin’s three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trialWenjia Lin0Xin-lin Chen1Qi Chen2Junmao Wen3Xinghua Chen4Guangzhou University of Traditional Chinese MedicineSchool of Basic Medical Science, Guangzhou University of Traditional Chinese MedicineGuangzhou University of Traditional Chinese MedicineGuangzhou University of Traditional Chinese MedicineThe First Affiliated Hospital, Guangzhou University of Traditional Chinese MedicineAbstract Background With an unclear pathomechanism, no confirmed treatment regimen has been established for chronic fatigue syndrome (CFS). Acupuncture is applied as an alternative therapy for CFS. As a kind of acupuncture therapy, Jin’s three-needle acupuncture (JTN) has been applied to treat CFS. However, few large-sample randomised controlled trials on JTN treatment for CFS have been reported. We designed this study to evaluate the efficacy and safety of JTN treatment for CFS. Method/design This study is a multicentre, single-blind, randomised controlled trial. Patients who meet the inclusion criteria will be recruited and randomly assigned to either the JTN treatment group or the basic acupuncture group. Both interventions will be conducted for five consecutive days per week and last for 2 weeks. The primary outcome is the effective rate based on the 14-item Fatigue Scale (FS-14) score. Other outcome measures include the Fatigue Assessment Scale (FAI), the Depression Status Inventory (DSI), and the Self-rating Anxiety Scale (SAS). Plasma adrenocorticotropic hormone (ACTH), plasma cortisol, and serum levels of IL-2 and IFN-γ will also be measured in this study. Adverse events will be observed and recorded for the safety evaluation. Discussion This study may help to identify the efficacy and safety of JTN acupuncture treatment for CFS. Trial registration Chinese Clinical Trial Registry, ID: ChiCTR-IOR-17011009. Registered on 29 March 2017.http://link.springer.com/article/10.1186/s13063-019-3243-5Chronic fatigue syndromeJin’s three-needle techniqueAcupunctureRandomised controlled trial |
| spellingShingle | Wenjia Lin Xin-lin Chen Qi Chen Junmao Wen Xinghua Chen Jin’s three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial Trials Chronic fatigue syndrome Jin’s three-needle technique Acupuncture Randomised controlled trial |
| title | Jin’s three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial |
| title_full | Jin’s three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial |
| title_fullStr | Jin’s three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial |
| title_full_unstemmed | Jin’s three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial |
| title_short | Jin’s three-needle acupuncture technique for chronic fatigue syndrome: a study protocol for a multicentre, randomized, controlled trial |
| title_sort | jin s three needle acupuncture technique for chronic fatigue syndrome a study protocol for a multicentre randomized controlled trial |
| topic | Chronic fatigue syndrome Jin’s three-needle technique Acupuncture Randomised controlled trial |
| url | http://link.springer.com/article/10.1186/s13063-019-3243-5 |
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