A molecular modeling study of novel aldose reductase (AR) inhibitors

A molecular modeling study of novel aldose reductase (AR) inhibitors

Aldose reductase (AR) is an enzyme of the polyol pathway implicated in long-term effect of diabetes mellitus. The development of new molecules as drugs for the inhibition of this enzyme is a growing area of research. Several <em>in vivo</em> and <em>in vitro</em> studies have...

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Bibliographic Details
Main Authors: Auwal Muhammad, Kanikar Muangchoo, Ibrahim A. Muhammad, Ya'u S. Ajingi, Aliyu M. Bello, Ibrahim Y. Muhammad, Tasi'u A. Mika'il, Rakiya Aliyu
Format: Article
Language:English
Published: AIMS Press 2020-12-01
Series:AIMS Biophysics
Subjects:
aldose reductase
bioactive compounds
binding energy
molecular docking
molecular dynamics
Online Access:http://www.aimspress.com/article/doi/10.3934/biophy.2020026?viewType=HTML

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