OPTN-TBK1 axis and a role for PLK1 in HSV-1 infection

OPTN-TBK1 axis and a role for PLK1 in HSV-1 infection

ABSTRACTTank-binding kinase 1 (TBK1) plays a pivotal role as a cellular factor in regulating the immune response against herpes simplex virus type 1 (HSV-1). TBK1’s role in defending against HSV-1 is attributed to its capacity to induce the type I interferon response. Recent discoveries emphasize TB...

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Bibliographic Details
Main Authors: Ilina Bhattacharya, Ipsita Volety, Deepak Shukla
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mBio
Subjects:
HSV-1
eye infection
OPTN
TBK1
PLK1
antiviral defense
Online Access:https://journals.asm.org/doi/10.1128/mbio.02715-23

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