Δ<sup>8</sup>-THC Induces Up-Regulation of Glutamatergic Pathway Genes in Differentiated SH-SY5Y: A Transcriptomic Study

Δ<sup>8</sup>-THC Induces Up-Regulation of Glutamatergic Pathway Genes in Differentiated SH-SY5Y: A Transcriptomic Study

Cannabinoids, natural or synthetic, have antidepressant, anxiolytic, anticonvulsant, and anti-psychotic properties. Cannabidiol (CBD) and delta-9-tetrahydrocannabinol (Δ<sup>9</sup>-THC) are the most studied cannabinoids, but recently, attention has turned towards minor cannabinoids. Del...

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Bibliographic Details
Main Authors: Ivan Anchesi, Giovanni Schepici, Luigi Chiricosta, Agnese Gugliandolo, Stefano Salamone, Diego Caprioglio, Federica Pollastro, Emanuela Mazzon
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
delta-8-tetrahydrocannabinol
SH-SY5Y cells
transcriptomic analysis
glutamatergic synapses
cholinergic synapses
dopaminergic synapses
Online Access:https://www.mdpi.com/1422-0067/24/11/9486

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