Metformin alleviates spinal cord injury by inhibiting nerve cell ferroptosis through upregulation of heme oxygenase-1 expression

Metformin alleviates spinal cord injury by inhibiting nerve cell ferroptosis through upregulation of heme oxygenase-1 expression

[INLINE:1] Previous studies have reported upregulation of heme oxygenase-1 in different central nervous system injury models. Heme oxygenase-1 plays a critical anti-inflammatory role and is essential for regulating cellular redox homeostasis. Metformin is a classic drug used to treat type 2 diabetes...

Full description

Bibliographic Details
Main Authors: Zhihua Wang, Wu Zhou, Zhixiong Zhang, Lulu Zhang, Meihua Li
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Neural Regeneration Research
Subjects:
acyl-coa synthetase long-chain family member 4; ferroptosis; glutathione peroxidase 4; heme oxygenase-1; inflammation; iron; lipid peroxidation; metformin; neuroprotection; spinal cord injury
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=9;spage=2041;epage=2049;aulast=

Internet

http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=9;spage=2041;epage=2049;aulast=

Similar Items