HLA and non-HLA genes and familial predisposition to autoimmune diseases in families with a child affected by type 1 diabetes.

HLA and non-HLA genes and familial predisposition to autoimmune diseases in families with a child affected by type 1 diabetes.

Genetic predisposition could be assumed to be causing clustering of autoimmunity in individuals and families. We tested whether HLA and non-HLA loci associate with such clustering of autoimmunity. We included 1,745 children with type 1 diabetes from the Finnish Pediatric Diabetes Register. Data on p...

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Detalles Bibliográficos
Main Authors: Anna Parkkola, Antti-Pekka Laine, Markku Karhunen, Taina Härkönen, Samppa J Ryhänen, Jorma Ilonen, Mikael Knip, Finnish Pediatric Diabetes Register
Formato: Artigo
Idioma:English
Publicado: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Acceso en liña:http://europepmc.org/articles/PMC5705143?pdf=render

Internet

http://europepmc.org/articles/PMC5705143?pdf=render

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