Vaccination against Paediatric Respiratory Pathogens
Acute respiratory infections (ARIs) are extremely common in children, especially those under 5 years old. They can lead to complications, super-infection, respiratory failure, and even compromised respiratory function in adulthood. For some of the responsible pathogens, vaccines are available. This...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2019-11-01
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| Series: | Vaccines |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-393X/7/4/168 |
| _version_ | 1828358332525576192 |
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| author | Sonia Bianchini Alberto Argentiero Barbara Camilloni Ettore Silvestri Anna Alunno Susanna Esposito |
| author_facet | Sonia Bianchini Alberto Argentiero Barbara Camilloni Ettore Silvestri Anna Alunno Susanna Esposito |
| author_sort | Sonia Bianchini |
| collection | DOAJ |
| description | Acute respiratory infections (ARIs) are extremely common in children, especially those under 5 years old. They can lead to complications, super-infection, respiratory failure, and even compromised respiratory function in adulthood. For some of the responsible pathogens, vaccines are available. This review reports current issues about vaccines against the main respiratory pathogens to highlight the available strategies to reduce the burden of paediatric respiratory disease. The optimal use of influenza, pneumococcal, pertussis and measles vaccines is required in order to reduce ARI burden. Vaccination coverage rates must be improved to achieve the full benefits of these vaccines. Recently, advances in the knowledge of respiratory syncytial virus structural biology and immunology as well as the development of new techniques to generate vaccine candidates have increased the number of promising vaccines even against this harmful pathogen. |
| first_indexed | 2024-04-14T03:28:20Z |
| format | Article |
| id | doaj.art-a9bb06110e8b4f7b96aa531c03b8732c |
| institution | Directory Open Access Journal |
| issn | 2076-393X |
| language | English |
| last_indexed | 2024-04-14T03:28:20Z |
| publishDate | 2019-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Vaccines |
| spelling | doaj.art-a9bb06110e8b4f7b96aa531c03b8732c2022-12-22T02:15:05ZengMDPI AGVaccines2076-393X2019-11-017416810.3390/vaccines7040168vaccines7040168Vaccination against Paediatric Respiratory PathogensSonia Bianchini0Alberto Argentiero1Barbara Camilloni2Ettore Silvestri3Anna Alunno4Susanna Esposito5Pediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, 06123 Perugia, ItalyPediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, 06123 Perugia, ItalyMicrobiology Unit, Department of Medicine, Università degli Studi di Perugia, 06123 Perugia, ItalyPediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, 06123 Perugia, ItalyMicrobiology Unit, Department of Medicine, Università degli Studi di Perugia, 06123 Perugia, ItalyPietro Barilla Children’s Hospital, Department of Medicine and Surgery, University of Parma, 43126 Parma, ItalyAcute respiratory infections (ARIs) are extremely common in children, especially those under 5 years old. They can lead to complications, super-infection, respiratory failure, and even compromised respiratory function in adulthood. For some of the responsible pathogens, vaccines are available. This review reports current issues about vaccines against the main respiratory pathogens to highlight the available strategies to reduce the burden of paediatric respiratory disease. The optimal use of influenza, pneumococcal, pertussis and measles vaccines is required in order to reduce ARI burden. Vaccination coverage rates must be improved to achieve the full benefits of these vaccines. Recently, advances in the knowledge of respiratory syncytial virus structural biology and immunology as well as the development of new techniques to generate vaccine candidates have increased the number of promising vaccines even against this harmful pathogen.https://www.mdpi.com/2076-393X/7/4/168respiratory pathogenvaccinechildrencomplicationoutbreakinfection |
| spellingShingle | Sonia Bianchini Alberto Argentiero Barbara Camilloni Ettore Silvestri Anna Alunno Susanna Esposito Vaccination against Paediatric Respiratory Pathogens Vaccines respiratory pathogen vaccine children complication outbreak infection |
| title | Vaccination against Paediatric Respiratory Pathogens |
| title_full | Vaccination against Paediatric Respiratory Pathogens |
| title_fullStr | Vaccination against Paediatric Respiratory Pathogens |
| title_full_unstemmed | Vaccination against Paediatric Respiratory Pathogens |
| title_short | Vaccination against Paediatric Respiratory Pathogens |
| title_sort | vaccination against paediatric respiratory pathogens |
| topic | respiratory pathogen vaccine children complication outbreak infection |
| url | https://www.mdpi.com/2076-393X/7/4/168 |
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