Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report

Small cell carcinomas are the most aggressive, highly malignant neuroendocrine tumors; among these, gastric small cell carcinoma (GSCC) is extremely rare. Here we report a case of a patient with primary GSCC, presenting as linitis plastic, who was diagnosed using endoscopic ultrasound (EUS)-guided b...

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Main Authors: Ra Ri Cha, Jin Kyu Cho, Wan Soo Kim, Jin Joo Kim, Jae Min Lee, Sang Soo Lee, Hyun Jin Kim
Format: Article
Language:English
Published: Korean Society of Gastrointestinal Endoscopy 2019-05-01
Series:Clinical Endoscopy
Subjects:
Online Access:http://www.e-ce.org/upload/pdf/ce-2018-114.pdf
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author Ra Ri Cha
Jin Kyu Cho
Wan Soo Kim
Jin Joo Kim
Jae Min Lee
Sang Soo Lee
Hyun Jin Kim
author_facet Ra Ri Cha
Jin Kyu Cho
Wan Soo Kim
Jin Joo Kim
Jae Min Lee
Sang Soo Lee
Hyun Jin Kim
author_sort Ra Ri Cha
collection DOAJ
description Small cell carcinomas are the most aggressive, highly malignant neuroendocrine tumors; among these, gastric small cell carcinoma (GSCC) is extremely rare. Here we report a case of a patient with primary GSCC, presenting as linitis plastic, who was diagnosed using endoscopic ultrasound (EUS)-guided biopsy. With undiagnosed linitis plastica, an 80-year-old woman was referred to our institution. Abdominal computed tomography revealed irregular wall thickening extending from the gastric body to the antrum. Endoscopy suspected to have Borrmann type IV advanced gastric cancer. EUS of the stomach showed diffuse submucosal thickening of the gastric wall, mainly the antrum. EUS-guided bite-on-bite biopsy confirmed the diagnosis of GSCC. In general, GSCC is difficult to diagnose and careful examination is necessary to determine the therapeutic strategy; however, EUS is particularly helpful in the differential diagnosis of a lesion presenting as linitis plastica.
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spelling doaj.art-a9bca8c2bf9f4eb4bca66bef41caee682023-10-02T00:24:29ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432019-05-0152327828210.5946/ce.2018.1147157Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case ReportRa Ri Cha0Jin Kyu Cho1Wan Soo Kim2Jin Joo Kim3Jae Min Lee4Sang Soo Lee5Hyun Jin Kim6 Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea Department of Surgery, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea Department of Internal Medicine, Gyeongsang National University Changwon Hospital, Changwon, KoreaSmall cell carcinomas are the most aggressive, highly malignant neuroendocrine tumors; among these, gastric small cell carcinoma (GSCC) is extremely rare. Here we report a case of a patient with primary GSCC, presenting as linitis plastic, who was diagnosed using endoscopic ultrasound (EUS)-guided biopsy. With undiagnosed linitis plastica, an 80-year-old woman was referred to our institution. Abdominal computed tomography revealed irregular wall thickening extending from the gastric body to the antrum. Endoscopy suspected to have Borrmann type IV advanced gastric cancer. EUS of the stomach showed diffuse submucosal thickening of the gastric wall, mainly the antrum. EUS-guided bite-on-bite biopsy confirmed the diagnosis of GSCC. In general, GSCC is difficult to diagnose and careful examination is necessary to determine the therapeutic strategy; however, EUS is particularly helpful in the differential diagnosis of a lesion presenting as linitis plastica.http://www.e-ce.org/upload/pdf/ce-2018-114.pdfExtrapulmonary small cell carcinomaEndosonographyLinitis plastica
spellingShingle Ra Ri Cha
Jin Kyu Cho
Wan Soo Kim
Jin Joo Kim
Jae Min Lee
Sang Soo Lee
Hyun Jin Kim
Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report
Clinical Endoscopy
Extrapulmonary small cell carcinoma
Endosonography
Linitis plastica
title Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report
title_full Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report
title_fullStr Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report
title_full_unstemmed Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report
title_short Primary Gastric Small Cell Carcinoma (Presenting as Linitis Plastica) Diagnosed Using Endoscopic Ultrasound-Guided Biopsy: A Case Report
title_sort primary gastric small cell carcinoma presenting as linitis plastica diagnosed using endoscopic ultrasound guided biopsy a case report
topic Extrapulmonary small cell carcinoma
Endosonography
Linitis plastica
url http://www.e-ce.org/upload/pdf/ce-2018-114.pdf
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