Biological potential of thiazolidinedione derivatives of synthetic origin
Abstract Thiazolidinediones are sulfur containing pentacyclic compounds that are widely found throughout nature in various forms. Thiazolidinedione nucleus is present in numerous biological compounds, e.g., anti-malarial, antimicrobial, anti-mycobacterium, anticonvulsant, antiviral, anticancer, anti...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2017-12-01
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| Series: | Chemistry Central Journal |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13065-017-0357-2 |
| _version_ | 1818589567661375488 |
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| author | Sucheta Sumit Tahlan Prabhakar Kumar Verma |
| author_facet | Sucheta Sumit Tahlan Prabhakar Kumar Verma |
| author_sort | Sucheta |
| collection | DOAJ |
| description | Abstract Thiazolidinediones are sulfur containing pentacyclic compounds that are widely found throughout nature in various forms. Thiazolidinedione nucleus is present in numerous biological compounds, e.g., anti-malarial, antimicrobial, anti-mycobacterium, anticonvulsant, antiviral, anticancer, anti-inflammatory, antioxidant, anti-HIV (human immunodeficiency virus) and antitubercular agent. However, owing to the swift development of new molecules containing this nucleus, many research reports have been generated in a brief span of time. Therefore seems to be a requirement to collect recent information in order to understand the current status of the thiazolidinedione nucleus in medicinal chemistry research, focusing in particular on the numerous attempts to synthesize and investigate new structural prototypes with more effective antidiabetic, antimicrobial, antioxidant, anti-inflammatory, anticancer and antitubercular activity. |
| first_indexed | 2024-12-16T09:42:42Z |
| format | Article |
| id | doaj.art-a9bf6f8d075244a4bc2028dd4304faf1 |
| institution | Directory Open Access Journal |
| issn | 1752-153X |
| language | English |
| last_indexed | 2024-12-16T09:42:42Z |
| publishDate | 2017-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Chemistry Central Journal |
| spelling | doaj.art-a9bf6f8d075244a4bc2028dd4304faf12022-12-21T22:36:13ZengBMCChemistry Central Journal1752-153X2017-12-0111112910.1186/s13065-017-0357-2Biological potential of thiazolidinedione derivatives of synthetic originSucheta0Sumit Tahlan1Prabhakar Kumar Verma2Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Maharshi Dayanand UniversityDepartment of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Maharshi Dayanand UniversityDepartment of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences, Maharshi Dayanand UniversityAbstract Thiazolidinediones are sulfur containing pentacyclic compounds that are widely found throughout nature in various forms. Thiazolidinedione nucleus is present in numerous biological compounds, e.g., anti-malarial, antimicrobial, anti-mycobacterium, anticonvulsant, antiviral, anticancer, anti-inflammatory, antioxidant, anti-HIV (human immunodeficiency virus) and antitubercular agent. However, owing to the swift development of new molecules containing this nucleus, many research reports have been generated in a brief span of time. Therefore seems to be a requirement to collect recent information in order to understand the current status of the thiazolidinedione nucleus in medicinal chemistry research, focusing in particular on the numerous attempts to synthesize and investigate new structural prototypes with more effective antidiabetic, antimicrobial, antioxidant, anti-inflammatory, anticancer and antitubercular activity.http://link.springer.com/article/10.1186/s13065-017-0357-2Thiazolidinedione derivativesAntidiabeticAntimicrobialAnti-inflammatory |
| spellingShingle | Sucheta Sumit Tahlan Prabhakar Kumar Verma Biological potential of thiazolidinedione derivatives of synthetic origin Chemistry Central Journal Thiazolidinedione derivatives Antidiabetic Antimicrobial Anti-inflammatory |
| title | Biological potential of thiazolidinedione derivatives of synthetic origin |
| title_full | Biological potential of thiazolidinedione derivatives of synthetic origin |
| title_fullStr | Biological potential of thiazolidinedione derivatives of synthetic origin |
| title_full_unstemmed | Biological potential of thiazolidinedione derivatives of synthetic origin |
| title_short | Biological potential of thiazolidinedione derivatives of synthetic origin |
| title_sort | biological potential of thiazolidinedione derivatives of synthetic origin |
| topic | Thiazolidinedione derivatives Antidiabetic Antimicrobial Anti-inflammatory |
| url | http://link.springer.com/article/10.1186/s13065-017-0357-2 |
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