Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib

Impact of clinical and molecular features on efficacy and outcome of patients with non-small cell lung cancer receiving second-line osimertinib

Abstract Background Although with the impressive efficacy, several patients showed intrinsic resistance or an unsatisfactory response to Osimertinib. We aim to explore the impact of clinical and molecular features on efficacy and outcome of patients with EGFR T790M-mutation non-small cell lung cance...

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Bibliographic Details
Main Authors: Ying Jin, Chen Lin, Xun Shi, Qiong He, Junrong Yan, Xinmin Yu, Ming Chen
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Cancer
Subjects:
Clinical and molecular features
Efficacy and outcome
EGFR T790M mutation
Non-small-cell lung cancer
Osimertinib
Online Access:https://doi.org/10.1186/s12885-022-09683-1

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