Enhanced Corrosion Resistance and Biological Properties of Ultrafine-Grained Ti15Zr5Cu Alloy

Titanium alloys are widely used in the biomedical field. To ensure their strength meets requirements in clinics, medical titanium alloys are generally alloyed with toxic Al and/or V elements, hence ensuring their long-term biological safety after implantation is a challenge. In our previous research...

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Main Authors: Hai Wang, Wenwei Gao, Xiyue Zhang, Yi Li, Shuyuan Zhang, Ling Ren, Ke Yang
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Metals
Subjects:
Online Access:https://www.mdpi.com/2075-4701/12/7/1144
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author Hai Wang
Wenwei Gao
Xiyue Zhang
Yi Li
Shuyuan Zhang
Ling Ren
Ke Yang
author_facet Hai Wang
Wenwei Gao
Xiyue Zhang
Yi Li
Shuyuan Zhang
Ling Ren
Ke Yang
author_sort Hai Wang
collection DOAJ
description Titanium alloys are widely used in the biomedical field. To ensure their strength meets requirements in clinics, medical titanium alloys are generally alloyed with toxic Al and/or V elements, hence ensuring their long-term biological safety after implantation is a challenge. In our previous research, we developed an ultrafine-grained Ti15Zr5Cu alloy without toxic elements while its mechanical properties were at the same level with the most widely used Ti6Al4V alloy. In order to promote the clinical application of the ultrafine-grained Ti15Zr5Cu alloy, herein we have systematically studied the hot deformation behaviors of the material as well as evaluated its corrosion resistance and biological properties. Results showed that when the as-quenched Ti15Zr5Cu alloy deformed at 0.05 ≤ <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mover><mi>ε</mi><mo>˙</mo></mover></mrow></semantics></math></inline-formula> ≤ 1, 730 °C ≤ T ≤ 750 °C, it not only possessed good workability but also can be converted into an equiaxed ultrafine-grained microstructure. Moreover, the material also exhibited better corrosion resistance, antibacterial properties and biocompatibility than the Ti15Zr alloy and the commercial pure Ti. The results of the present study help lay a foundation for the development of a new generation of medical titanium alloys.
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spelling doaj.art-a9c59f92cacd4a868ddbc3363c0dbeb42023-12-01T22:26:24ZengMDPI AGMetals2075-47012022-07-01127114410.3390/met12071144Enhanced Corrosion Resistance and Biological Properties of Ultrafine-Grained Ti15Zr5Cu AlloyHai Wang0Wenwei Gao1Xiyue Zhang2Yi Li3Shuyuan Zhang4Ling Ren5Ke Yang6Shi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaShi-Changxu Innovation Center for Advanced Materials, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, ChinaTitanium alloys are widely used in the biomedical field. To ensure their strength meets requirements in clinics, medical titanium alloys are generally alloyed with toxic Al and/or V elements, hence ensuring their long-term biological safety after implantation is a challenge. In our previous research, we developed an ultrafine-grained Ti15Zr5Cu alloy without toxic elements while its mechanical properties were at the same level with the most widely used Ti6Al4V alloy. In order to promote the clinical application of the ultrafine-grained Ti15Zr5Cu alloy, herein we have systematically studied the hot deformation behaviors of the material as well as evaluated its corrosion resistance and biological properties. Results showed that when the as-quenched Ti15Zr5Cu alloy deformed at 0.05 ≤ <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mover><mi>ε</mi><mo>˙</mo></mover></mrow></semantics></math></inline-formula> ≤ 1, 730 °C ≤ T ≤ 750 °C, it not only possessed good workability but also can be converted into an equiaxed ultrafine-grained microstructure. Moreover, the material also exhibited better corrosion resistance, antibacterial properties and biocompatibility than the Ti15Zr alloy and the commercial pure Ti. The results of the present study help lay a foundation for the development of a new generation of medical titanium alloys.https://www.mdpi.com/2075-4701/12/7/1144ultrafine-grainedhot workabilitycorrosion resistanceantibacterial propertiescytotoxicity
spellingShingle Hai Wang
Wenwei Gao
Xiyue Zhang
Yi Li
Shuyuan Zhang
Ling Ren
Ke Yang
Enhanced Corrosion Resistance and Biological Properties of Ultrafine-Grained Ti15Zr5Cu Alloy
Metals
ultrafine-grained
hot workability
corrosion resistance
antibacterial properties
cytotoxicity
title Enhanced Corrosion Resistance and Biological Properties of Ultrafine-Grained Ti15Zr5Cu Alloy
title_full Enhanced Corrosion Resistance and Biological Properties of Ultrafine-Grained Ti15Zr5Cu Alloy
title_fullStr Enhanced Corrosion Resistance and Biological Properties of Ultrafine-Grained Ti15Zr5Cu Alloy
title_full_unstemmed Enhanced Corrosion Resistance and Biological Properties of Ultrafine-Grained Ti15Zr5Cu Alloy
title_short Enhanced Corrosion Resistance and Biological Properties of Ultrafine-Grained Ti15Zr5Cu Alloy
title_sort enhanced corrosion resistance and biological properties of ultrafine grained ti15zr5cu alloy
topic ultrafine-grained
hot workability
corrosion resistance
antibacterial properties
cytotoxicity
url https://www.mdpi.com/2075-4701/12/7/1144
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