ECoG activity distribution patterns detects global cortical responses following weak tactile inputs
Summary: Many studies have suggested that the neocortex operates as a global network of functionally interconnected neurons, indicating that any sensory input could shift activity distributions across the whole brain. A tool assessing the activity distribution across cortical regions with high tempo...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-04-01
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| Series: | iScience |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004224005595 |
| _version_ | 1797267200948568064 |
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| author | Astrid Mellbin Udaya Rongala Henrik Jörntell Fredrik Bengtsson |
| author_facet | Astrid Mellbin Udaya Rongala Henrik Jörntell Fredrik Bengtsson |
| author_sort | Astrid Mellbin |
| collection | DOAJ |
| description | Summary: Many studies have suggested that the neocortex operates as a global network of functionally interconnected neurons, indicating that any sensory input could shift activity distributions across the whole brain. A tool assessing the activity distribution across cortical regions with high temporal resolution could then potentially detect subtle changes that may pass unnoticed in regionalized analyses. We used eight-channel, distributed electrocorticogram (ECoG) recordings to analyze changes in global activity distribution caused by single pulse electrical stimulations of the paw. We analyzed the temporally evolving patterns of the activity distributions using principal component analysis (PCA). We found that the localized tactile stimulation caused clearly measurable changes in global ECoG activity distribution. These changes in signal activity distribution patterns were detectable across a small number of ECoG channels, even when excluding the somatosensory cortex, suggesting that the method has high sensitivity, potentially making it applicable to human electroencephalography (EEG) for detection of pathological changes. |
| first_indexed | 2024-04-25T01:12:49Z |
| format | Article |
| id | doaj.art-a9c5a38e1f12426a9bbf79357a4c8826 |
| institution | Directory Open Access Journal |
| issn | 2589-0042 |
| language | English |
| last_indexed | 2024-04-25T01:12:49Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | iScience |
| spelling | doaj.art-a9c5a38e1f12426a9bbf79357a4c88262024-03-10T05:12:33ZengElsevieriScience2589-00422024-04-01274109338ECoG activity distribution patterns detects global cortical responses following weak tactile inputsAstrid Mellbin0Udaya Rongala1Henrik Jörntell2Fredrik Bengtsson3Neural Basis of Sensorimotor Control, Department of Experimental Medical Science, Biomedical Centre, Lund University, SE-223 62 Lund, Sweden; Corresponding authorNeural Basis of Sensorimotor Control, Department of Experimental Medical Science, Biomedical Centre, Lund University, SE-223 62 Lund, SwedenNeural Basis of Sensorimotor Control, Department of Experimental Medical Science, Biomedical Centre, Lund University, SE-223 62 Lund, SwedenNeural Basis of Sensorimotor Control, Department of Experimental Medical Science, Biomedical Centre, Lund University, SE-223 62 Lund, SwedenSummary: Many studies have suggested that the neocortex operates as a global network of functionally interconnected neurons, indicating that any sensory input could shift activity distributions across the whole brain. A tool assessing the activity distribution across cortical regions with high temporal resolution could then potentially detect subtle changes that may pass unnoticed in regionalized analyses. We used eight-channel, distributed electrocorticogram (ECoG) recordings to analyze changes in global activity distribution caused by single pulse electrical stimulations of the paw. We analyzed the temporally evolving patterns of the activity distributions using principal component analysis (PCA). We found that the localized tactile stimulation caused clearly measurable changes in global ECoG activity distribution. These changes in signal activity distribution patterns were detectable across a small number of ECoG channels, even when excluding the somatosensory cortex, suggesting that the method has high sensitivity, potentially making it applicable to human electroencephalography (EEG) for detection of pathological changes.http://www.sciencedirect.com/science/article/pii/S2589004224005595NeuroscienceSensory neuroscienceCognitive neuroscience |
| spellingShingle | Astrid Mellbin Udaya Rongala Henrik Jörntell Fredrik Bengtsson ECoG activity distribution patterns detects global cortical responses following weak tactile inputs iScience Neuroscience Sensory neuroscience Cognitive neuroscience |
| title | ECoG activity distribution patterns detects global cortical responses following weak tactile inputs |
| title_full | ECoG activity distribution patterns detects global cortical responses following weak tactile inputs |
| title_fullStr | ECoG activity distribution patterns detects global cortical responses following weak tactile inputs |
| title_full_unstemmed | ECoG activity distribution patterns detects global cortical responses following weak tactile inputs |
| title_short | ECoG activity distribution patterns detects global cortical responses following weak tactile inputs |
| title_sort | ecog activity distribution patterns detects global cortical responses following weak tactile inputs |
| topic | Neuroscience Sensory neuroscience Cognitive neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2589004224005595 |
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