Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine – A retrospective cohort study
Background: Kabasura Kudineer (KSK) is a Siddha polyherbal decoction recommended by the Ministry of AYUSH and the Tamil Nadu government to prevent and manage COVID-19 in India. Objective(s): We aimed to determine the outcome of integrated therapy for COVID-19 using KSK in virologic clearance and len...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-04-01
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| Series: | Journal of Ayurveda and Integrative Medicine |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0975947621001182 |
| _version_ | 1811330858797236224 |
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| author | Ramaswamy Meenakumari Karuppiah Thangaraj Arunachalam Sundaram Malayappan Meenakshi Sundaram Ponnappan Shanmugapriya Andi Mariappan Melvin George Venkatesan Suba Elumalai Rajalakshmi Muthappan Sendhilkumar |
| author_facet | Ramaswamy Meenakumari Karuppiah Thangaraj Arunachalam Sundaram Malayappan Meenakshi Sundaram Ponnappan Shanmugapriya Andi Mariappan Melvin George Venkatesan Suba Elumalai Rajalakshmi Muthappan Sendhilkumar |
| author_sort | Ramaswamy Meenakumari |
| collection | DOAJ |
| description | Background: Kabasura Kudineer (KSK) is a Siddha polyherbal decoction recommended by the Ministry of AYUSH and the Tamil Nadu government to prevent and manage COVID-19 in India. Objective(s): We aimed to determine the outcome of integrated therapy for COVID-19 using KSK in virologic clearance and length of hospital stay. Materials and methods: It was a single-centre, retrospective cohort study. We included the COVID-19 patients admitted to SRM Medical College Hospital and Research Centre, Chennai, during May–June 2020. KSK was administered along with the standard of care for all the patients. We collected data pertaining to demographic, clinical, and laboratory parameters and presented as frequencies and proportions. Results: We collected 204 COVID-19 positive patients’ data. The mean (SD) age was 39.5 (13.4) years with a range of 13–79. Majority of the patients were male (n = 157; 77%), 28% (n = 58) had any co-morbidities, and 61% (n = 131) had mild symptoms. Fever (n = 57; 27.9%) and cough (n = 53; 25.9%) were the commonly reported symptoms. Paracetamol (n = 135; 66.7%) and Zincovit (n = 197, 96.6%) were the commonly administered medicines along with KSK. About 74% of asymptomatic (n = 54) and 65% of mild symptomatic (n = 85) patients turned negative for COVID-19 in RT-PCR within 4–7 days. There was a significant difference in the blood parameters (p < 0.05) after the integrated treatment. Conclusion: The use of KSK with standard care of treatment in COVID-19 treatment had notable results in the duration taken for virologic clearance, thereby reducing the length of hospital stay and improvement in laboratory parameters. |
| first_indexed | 2024-04-13T16:09:13Z |
| format | Article |
| id | doaj.art-a9c5ad347943444680e90ee4c4832303 |
| institution | Directory Open Access Journal |
| issn | 0975-9476 |
| language | English |
| last_indexed | 2024-04-13T16:09:13Z |
| publishDate | 2022-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Ayurveda and Integrative Medicine |
| spelling | doaj.art-a9c5ad347943444680e90ee4c48323032022-12-22T02:40:18ZengElsevierJournal of Ayurveda and Integrative Medicine0975-94762022-04-01132100470Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine – A retrospective cohort studyRamaswamy Meenakumari0Karuppiah Thangaraj1Arunachalam Sundaram2Malayappan Meenakshi Sundaram3Ponnappan Shanmugapriya4Andi Mariappan5Melvin George6Venkatesan Suba7Elumalai Rajalakshmi8Muthappan Sendhilkumar9National Institute of Siddha (NIS), Tambaram Sanatorium, Chennai, Tamil Nadu, India; Corresponding author.SRM Medical College, Kattankulathur, Chennai, Tamil Nadu, IndiaSRM Medical College, Kattankulathur, Chennai, Tamil Nadu, IndiaNational Institute of Siddha (NIS), Tambaram Sanatorium, Chennai, Tamil Nadu, IndiaNational Institute of Siddha (NIS), Tambaram Sanatorium, Chennai, Tamil Nadu, IndiaNational Institute of Siddha (NIS), Tambaram Sanatorium, Chennai, Tamil Nadu, IndiaSRM Medical College, Kattankulathur, Chennai, Tamil Nadu, IndiaNational Institute of Siddha (NIS), Tambaram Sanatorium, Chennai, Tamil Nadu, IndiaICMR-National Institute of Epidemiology (ICMR-NIE), Chennai, Tamil Nadu, IndiaICMR-National Institute of Epidemiology (ICMR-NIE), Chennai, Tamil Nadu, IndiaBackground: Kabasura Kudineer (KSK) is a Siddha polyherbal decoction recommended by the Ministry of AYUSH and the Tamil Nadu government to prevent and manage COVID-19 in India. Objective(s): We aimed to determine the outcome of integrated therapy for COVID-19 using KSK in virologic clearance and length of hospital stay. Materials and methods: It was a single-centre, retrospective cohort study. We included the COVID-19 patients admitted to SRM Medical College Hospital and Research Centre, Chennai, during May–June 2020. KSK was administered along with the standard of care for all the patients. We collected data pertaining to demographic, clinical, and laboratory parameters and presented as frequencies and proportions. Results: We collected 204 COVID-19 positive patients’ data. The mean (SD) age was 39.5 (13.4) years with a range of 13–79. Majority of the patients were male (n = 157; 77%), 28% (n = 58) had any co-morbidities, and 61% (n = 131) had mild symptoms. Fever (n = 57; 27.9%) and cough (n = 53; 25.9%) were the commonly reported symptoms. Paracetamol (n = 135; 66.7%) and Zincovit (n = 197, 96.6%) were the commonly administered medicines along with KSK. About 74% of asymptomatic (n = 54) and 65% of mild symptomatic (n = 85) patients turned negative for COVID-19 in RT-PCR within 4–7 days. There was a significant difference in the blood parameters (p < 0.05) after the integrated treatment. Conclusion: The use of KSK with standard care of treatment in COVID-19 treatment had notable results in the duration taken for virologic clearance, thereby reducing the length of hospital stay and improvement in laboratory parameters.http://www.sciencedirect.com/science/article/pii/S0975947621001182SiddhaKabasura kudineerCOVID-19AYUSHTraditional medicine |
| spellingShingle | Ramaswamy Meenakumari Karuppiah Thangaraj Arunachalam Sundaram Malayappan Meenakshi Sundaram Ponnappan Shanmugapriya Andi Mariappan Melvin George Venkatesan Suba Elumalai Rajalakshmi Muthappan Sendhilkumar Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine – A retrospective cohort study Journal of Ayurveda and Integrative Medicine Siddha Kabasura kudineer COVID-19 AYUSH Traditional medicine |
| title | Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine – A retrospective cohort study |
| title_full | Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine – A retrospective cohort study |
| title_fullStr | Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine – A retrospective cohort study |
| title_full_unstemmed | Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine – A retrospective cohort study |
| title_short | Clinical outcomes among COVID-19 patients managed with modern and traditional Siddha medicine – A retrospective cohort study |
| title_sort | clinical outcomes among covid 19 patients managed with modern and traditional siddha medicine a retrospective cohort study |
| topic | Siddha Kabasura kudineer COVID-19 AYUSH Traditional medicine |
| url | http://www.sciencedirect.com/science/article/pii/S0975947621001182 |
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