The Association between Inefficient Repair of DNA Double-Strand Breaks and Common Polymorphisms of the HRR and NHEJ Repair Genes in Patients with Rheumatoid Arthritis

The Association between Inefficient Repair of DNA Double-Strand Breaks and Common Polymorphisms of the HRR and NHEJ Repair Genes in Patients with Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation affecting up to 2.0% of adults around the world. The molecular background of RA has not yet been fully elucidated, but RA is classified as a disease in which the genetic background is one of the most significant...

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Bibliographic Details
Main Authors: Grzegorz Galita, Joanna Sarnik, Olga Brzezinska, Tomasz Budlewski, Marta Poplawska, Sebastian Sakowski, Grzegorz Dudek, Ireneusz Majsterek, Joanna Makowska, Tomasz Poplawski
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
rheumatoid arthritis
comet assay
DNA double-strand break
DNA repair
single-nucleotide polymorphism
RAD50
Online Access:https://www.mdpi.com/1422-0067/25/5/2619

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