Cell-free chromatin particles released from dying cells inflict mitochondrial damage and ROS production in living cells

Cell-free chromatin particles released from dying cells inflict mitochondrial damage and ROS production in living cells

Abstract Mitochondrial damage and the resultant oxidative stress are associated with neurodegenerative diseases, ageing, and cancer. However, the triggers of mitochondrial damage remain unclear. We previously reported that cell-free chromatin particles (cfChPs) released from the billions of cells th...

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Hlavní autoři: Gorantla V. Raghuram, Bhabesh Kumar Tripathy, Kartikeya Avadhani, Snehal Shabrish, Naveen Kumar Khare, Relestina Lopes, Kavita Pal, Indraneel Mittra
Médium: Článek
Jazyk:English
Vydáno: Nature Publishing Group 2024-01-01
Edice:Cell Death Discovery
On-line přístup:https://doi.org/10.1038/s41420-023-01728-z

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