Outcome and complications of living donor pediatric renal transplantation: Experience from a tertiary care center
Introduction: We retrospectively reviewed the patient characteristics, outcome, and complications of renal transplantation in pediatric age group performed at our center and compared the results with various centers in India and other developed countries. Materials and Methods: Patients younger than...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Indian Journal of Urology |
| Online Access: | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2017;volume=33;issue=3;spage=221;epage=225;aulast=Bijalwan |
| _version_ | 1818681710669201408 |
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| author | Priyank Bijalwan Kalavampara V Sanjeevan Anil Mathew T Balagopal Nair |
| author_facet | Priyank Bijalwan Kalavampara V Sanjeevan Anil Mathew T Balagopal Nair |
| author_sort | Priyank Bijalwan |
| collection | DOAJ |
| description | Introduction: We retrospectively reviewed the patient characteristics, outcome, and complications of renal transplantation in pediatric age group performed at our center and compared the results with various centers in India and other developed countries.
Materials and Methods: Patients younger than eighteen years of age who underwent renal transplantation from 2003 to 2014 at our institute were reviewed. Demographic data of the transplant recipients and donors, etiology of ESRD, mode of dialysis, surgical details of renal transplantation, immunosuppression, medical and surgical complications, and post-transplant follow-up were assessed. Graft survival was determined at 1, 3 and 5 years post-transplant. All data collected were entered into Microsoft excel program and analyzed using SPSS 20. Kaplan–Meier method was applied to determine the graft survival at 1, 3, and 5 years. The log-rank test was applied to test the statistical significance of the difference in survival between groups.
Results: Thirty-two children underwent transplantation comprising of 18 females and 14 males. The mean age was 14.5 years (range 10–17 years). The primary cause of renal failure was glomerular diseases in 53% (17/32) of patients. Seventeen postsurgical complications were noted in our series. Two grafts were lost over a follow-up of 5 years. The 1, 3, and 5 year graft survival rates were 96.7%, 92.9%, and 85%, respectively. There was no mortality.
Conclusion: The etiology of ESRD in our region is different from that of developed countries. The mean age at which children undergo renal transplantation is higher. Graft survival at our center is comparable to that of developed nations. Renal transplantation can be safely performed in children with ESRD. |
| first_indexed | 2024-12-17T10:07:17Z |
| format | Article |
| id | doaj.art-a9cdb4fd0af04ebeb109b9efe99543c3 |
| institution | Directory Open Access Journal |
| issn | 0970-1591 1998-3824 |
| language | English |
| last_indexed | 2024-12-17T10:07:17Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Urology |
| spelling | doaj.art-a9cdb4fd0af04ebeb109b9efe99543c32022-12-21T21:53:08ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242017-01-0133322122510.4103/iju.IJU_382_16Outcome and complications of living donor pediatric renal transplantation: Experience from a tertiary care centerPriyank BijalwanKalavampara V SanjeevanAnil MathewT Balagopal NairIntroduction: We retrospectively reviewed the patient characteristics, outcome, and complications of renal transplantation in pediatric age group performed at our center and compared the results with various centers in India and other developed countries. Materials and Methods: Patients younger than eighteen years of age who underwent renal transplantation from 2003 to 2014 at our institute were reviewed. Demographic data of the transplant recipients and donors, etiology of ESRD, mode of dialysis, surgical details of renal transplantation, immunosuppression, medical and surgical complications, and post-transplant follow-up were assessed. Graft survival was determined at 1, 3 and 5 years post-transplant. All data collected were entered into Microsoft excel program and analyzed using SPSS 20. Kaplan–Meier method was applied to determine the graft survival at 1, 3, and 5 years. The log-rank test was applied to test the statistical significance of the difference in survival between groups. Results: Thirty-two children underwent transplantation comprising of 18 females and 14 males. The mean age was 14.5 years (range 10–17 years). The primary cause of renal failure was glomerular diseases in 53% (17/32) of patients. Seventeen postsurgical complications were noted in our series. Two grafts were lost over a follow-up of 5 years. The 1, 3, and 5 year graft survival rates were 96.7%, 92.9%, and 85%, respectively. There was no mortality. Conclusion: The etiology of ESRD in our region is different from that of developed countries. The mean age at which children undergo renal transplantation is higher. Graft survival at our center is comparable to that of developed nations. Renal transplantation can be safely performed in children with ESRD.http://www.indianjurol.com/article.asp?issn=0970-1591;year=2017;volume=33;issue=3;spage=221;epage=225;aulast=Bijalwan |
| spellingShingle | Priyank Bijalwan Kalavampara V Sanjeevan Anil Mathew T Balagopal Nair Outcome and complications of living donor pediatric renal transplantation: Experience from a tertiary care center Indian Journal of Urology |
| title | Outcome and complications of living donor pediatric renal transplantation: Experience from a tertiary care center |
| title_full | Outcome and complications of living donor pediatric renal transplantation: Experience from a tertiary care center |
| title_fullStr | Outcome and complications of living donor pediatric renal transplantation: Experience from a tertiary care center |
| title_full_unstemmed | Outcome and complications of living donor pediatric renal transplantation: Experience from a tertiary care center |
| title_short | Outcome and complications of living donor pediatric renal transplantation: Experience from a tertiary care center |
| title_sort | outcome and complications of living donor pediatric renal transplantation experience from a tertiary care center |
| url | http://www.indianjurol.com/article.asp?issn=0970-1591;year=2017;volume=33;issue=3;spage=221;epage=225;aulast=Bijalwan |
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