Lipopolysaccharide induces human pulmonary micro-vascular endothelial apoptosis via the YAP signaling pathway

Lipopolysaccharide induces human pulmonary micro-vascular endothelial apoptosis via the YAP signaling pathway

Gram-negative bacterial lipopolysaccharide (LPS) induces a pathologic increase in lung vascular leakage under septic conditions. LPS-induced human pulmonary micro-vascular endothelial cell (HPMEC) apoptosis launches and aggravates micro-vascular hyper-permeability and acute lung injury (ALI). Previo...

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Bibliographic Details
Main Authors: Lei Yi, Xiaoqin Huang, Feng Guo, Zengding Zhou, Mengling Chang, Jiajun Tang, Jingning Huan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Apoptosis
Endothelial Cells
lipopolysaccharide
p73
yes-associated protein
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00133/full

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