Identification of PARP-1, Histone H1 and SIRT-1 as New Regulators of Breast Cancer-Related Aromatase Promoter I.3/II
Paracrine interactions between malignant estrogen receptor positive (ER<sup>+</sup>) breast cancer cells and breast adipose fibroblasts (BAFs) stimulate estrogen biosynthesis by aromatase in BAFs. In breast cancer, mainly the cAMP-responsive promoter I.3/II-region mediates excessive arom...
Main Authors: | Alexander Kaiser, Thomas Krüger, Gabriele Eiselt, Joachim Bechler, Olaf Kniemeyer, Otmar Huber, Martin Schmidt |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-02-01
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Series: | Cells |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4409/9/2/427 |
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