Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway

Promotion effect of FGF23 on osteopenia in congenital scoliosis through FGFr3/TNAP/OPN pathway

Abstract. Background:. Congenital scoliosis (CS) is a complex spinal malformation of unknown etiology with abnormal bone metabolism. Fibroblast growth factor 23 (FGF23), secreted by osteoblasts and osteocytes, can inhibit bone formation and mineralization. This research aims to investigate the rela...

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Bibliographic Details
Main Authors: Hongqi Zhang, Gang Xiang, Jiong Li, Sihan He, Yunjia Wang, Ang Deng, Yuxiang Wang, Chaofeng Guo, Xiuyuan Hao
Format: Article
Language:English
Published: Wolters Kluwer 2023-06-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000002690

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