Synergistic and antagonistic drug interactions in the treatment of systemic fungal infections
Invasive fungal infections cause 1.6 million deaths annually, primarily in immunocompromised individuals. Mortality rates are as high as 90% due to limited treatments. The azole class antifungal, fluconazole, is widely available and has multi-species activity but only inhibits growth instead of kill...
Main Authors: | Morgan A Wambaugh, Steven T Denham, Magali Ayala, Brianna Brammer, Miekan A Stonhill, Jessica CS Brown |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/54160 |
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