Extensive bullous lichen sclerosus et atrophicus
Abstract Lichen sclerosus et atrophicus is a chronic disease of unknown etiology characterized by atrophic and sclerotic plaques in both genital and extragenital regions. Extensive bullous lichen sclerosus et atrophicus (BLSA) is a severe variant of the disease with no widely accepted treatment. We...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Dermatologia
2016-10-01
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| Series: | Anais Brasileiros de Dermatologia |
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| Online Access: | http://www.scielo.br/pdf/abd/v91n5s1/0365-0596-abd-91-05-s1-0081.pdf |
| _version_ | 1798016276174471168 |
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| author | Jelica Vukicevic |
| author_facet | Jelica Vukicevic |
| author_sort | Jelica Vukicevic |
| collection | DOAJ |
| description | Abstract Lichen sclerosus et atrophicus is a chronic disease of unknown etiology characterized by atrophic and sclerotic plaques in both genital and extragenital regions. Extensive bullous lichen sclerosus et atrophicus (BLSA) is a severe variant of the disease with no widely accepted treatment. We present a 63-year-old woman with extensive extragenital, ivory-colored, atrophic plaques on her trunk and extremities and disseminated hemorrhagic bullae. The patient was unsuccessfully treated with standard topical corticosteroid therapy, doxycycline and chloroquine. According to the literature, there is little evidence of the efficacy of doxycycline and hydroxychloroquine in the treatment of BLSA. We report a rare case of extensive BLSA that is unresponsive to these drugs. |
| first_indexed | 2024-04-11T15:48:21Z |
| format | Article |
| id | doaj.art-a9d924a94acf41539cb71ae4e98ca71a |
| institution | Directory Open Access Journal |
| issn | 0365-0596 |
| language | English |
| last_indexed | 2024-04-11T15:48:21Z |
| publishDate | 2016-10-01 |
| publisher | Sociedade Brasileira de Dermatologia |
| record_format | Article |
| series | Anais Brasileiros de Dermatologia |
| spelling | doaj.art-a9d924a94acf41539cb71ae4e98ca71a2022-12-22T04:15:28ZengSociedade Brasileira de DermatologiaAnais Brasileiros de Dermatologia0365-05962016-10-01915 suppl 1818310.1590/abd1806-4841.20164398Extensive bullous lichen sclerosus et atrophicusJelica VukicevicAbstract Lichen sclerosus et atrophicus is a chronic disease of unknown etiology characterized by atrophic and sclerotic plaques in both genital and extragenital regions. Extensive bullous lichen sclerosus et atrophicus (BLSA) is a severe variant of the disease with no widely accepted treatment. We present a 63-year-old woman with extensive extragenital, ivory-colored, atrophic plaques on her trunk and extremities and disseminated hemorrhagic bullae. The patient was unsuccessfully treated with standard topical corticosteroid therapy, doxycycline and chloroquine. According to the literature, there is little evidence of the efficacy of doxycycline and hydroxychloroquine in the treatment of BLSA. We report a rare case of extensive BLSA that is unresponsive to these drugs.http://www.scielo.br/pdf/abd/v91n5s1/0365-0596-abd-91-05-s1-0081.pdfBlisterChloroquineDoxycyclineLichen sclerosus et atrophicusHydroxychloroquine |
| spellingShingle | Jelica Vukicevic Extensive bullous lichen sclerosus et atrophicus Anais Brasileiros de Dermatologia Blister Chloroquine Doxycycline Lichen sclerosus et atrophicus Hydroxychloroquine |
| title | Extensive bullous lichen sclerosus et atrophicus |
| title_full | Extensive bullous lichen sclerosus et atrophicus |
| title_fullStr | Extensive bullous lichen sclerosus et atrophicus |
| title_full_unstemmed | Extensive bullous lichen sclerosus et atrophicus |
| title_short | Extensive bullous lichen sclerosus et atrophicus |
| title_sort | extensive bullous lichen sclerosus et atrophicus |
| topic | Blister Chloroquine Doxycycline Lichen sclerosus et atrophicus Hydroxychloroquine |
| url | http://www.scielo.br/pdf/abd/v91n5s1/0365-0596-abd-91-05-s1-0081.pdf |
| work_keys_str_mv | AT jelicavukicevic extensivebullouslichensclerosusetatrophicus |