Host Lung Environment Limits Aspergillus fumigatus Germination through an SskA-Dependent Signaling Response

Host Lung Environment Limits Aspergillus fumigatus Germination through an SskA-Dependent Signaling Response

ABSTRACT Aspergillus fumigatus isolates display significant heterogeneity in growth, virulence, pathology, and inflammatory potential in multiple murine models of invasive aspergillosis. Previous studies have linked the initial germination of a fungal isolate in the airways to the inflammatory and p...

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Bibliographic Details
Main Authors: Marina E. Kirkland, McKenzie Stannard, Caitlin H. Kowalski, Dallas Mould, Alayna Caffrey-Carr, Rachel M. Temple, Brandon S. Ross, Lotus A. Lofgren, Jason E. Stajich, Robert A. Cramer, Joshua J. Obar
Format: Article
Language:English
Published: American Society for Microbiology 2021-12-01
Series:mSphere
Subjects:
Aspergillus fumigatus
aspergillosis
germination
inflammation
Online Access:https://journals.asm.org/doi/10.1128/msphere.00922-21

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