Immunolipidomics Reveals a Globoside Network During the Resolution of Pro-Inflammatory Response in Human Macrophages

Immunolipidomics Reveals a Globoside Network During the Resolution of Pro-Inflammatory Response in Human Macrophages

Toll-like receptor 4 (TLR4)-mediated changes in macrophages reshape intracellular lipid pools to coordinate an effective innate immune response. Although this has been previously well-studied in different model systems, it remains incompletely understood in primary human macrophages. Here we report...

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Bibliographic Details
Main Authors: Sneha Muralidharan, Federico Torta, Michelle K. Lin, Antoni Olona, Marta Bagnati, Aida Moreno-Moral, Jeong-Hun Ko, Shanshan Ji, Bo Burla, Markus R. Wenk, Hosana G. Rodrigues, Enrico Petretto, Jacques Behmoaras
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
lipidomics
human macrophages
transcriptomics
globosides
network analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.926220/full

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