Sex-Specific Transcriptomic Signatures in Brain Regions Critical for Neuropathic Pain-Induced Depression

Sex-Specific Transcriptomic Signatures in Brain Regions Critical for Neuropathic Pain-Induced Depression

Neuropathic pain is a chronic debilitating condition with a high comorbidity with depression. Clinical reports and animal studies have suggested that both the medial prefrontal cortex (mPFC) and the anterior cingulate cortex (ACC) are critically implicated in regulating the affective symptoms of neu...

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Bibliographic Details
Main Authors: Weiping Dai, Shuying Huang, Yuan Luo, Xin Cheng, Pei Xia, Mengqian Yang, Panwu Zhao, Yingying Zhang, Wei-Jye Lin, Xiaojing Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Molecular Neuroscience
Subjects:
neuropathic pain
sex-differences
depression
medial prefrontal cortex
anterior cingulate cortex
RNA sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.886916/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.886916/full

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