Variants in the 15q24/25 locus associate with lung function decline in active smokers.

Variants in the 15q24/25 locus associate with lung function decline in active smokers.

Genetic variation in nicotinic acetylcholine receptor subunit genes (nAChRs) is associated with lung function level and chronic obstructive pulmonary disease (COPD). It is unknown whether these variants also predispose to an accelerated lung function decline. We investigated the association of nAChR...

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Main Authors: Firdaus A A Mohamed Hoesein, Els Wauters, Wim Janssens, Harry J M Groen, Joanna Smolonska, Cisca Wijmenga, Dirkje S Postma, H Marike Boezen, Pim A De Jong, Marc Decramer, Jan-Willem J Lammers, Diether Lambrechts, Pieter Zanen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23349703/pdf/?tool=EBI

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