3′-Sialyllactose Protects SW1353 Chondrocytic Cells From Interleukin-1β-Induced Oxidative Stress and Inflammation

3′-Sialyllactose Protects SW1353 Chondrocytic Cells From Interleukin-1β-Induced Oxidative Stress and Inflammation

Osteoarthritis (OA) is a major degenerative joint disease. Oxidative stress and inflammation play key roles in the pathogenesis of OA. 3′-Sialyllactose (3′-SL) is derived from human milk and is known to regulate a variety of biological functions related to immune homeostasis. This study aimed to inv...

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Bibliographic Details
Main Authors: Ahreum Baek, So Hee Jung, Soonil Pyo, Soo Yeon Kim, Seongmoon Jo, Lila Kim, Eun Young Lee, Sung Hoon Kim, Sung-Rae Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
osteoarthritis
3′-sialyllactose
oxidative stress
inflammation
apoptosis
matrix metalloproteinases
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.609817/full

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