Inhibitory Effect of P22077 on Airway Inflammation in Rats with COPD and Its Mechanism

Inhibitory Effect of P22077 on Airway Inflammation in Rats with COPD and Its Mechanism

Di Zeng,1,&ast; Wenbo Zhang,2,&ast; Xiaoju Chen,3 Guochun Ou,4 Yuewei Huang,2 Chengxiu Yu2 1Department of General Practice, The Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, 637000, People’s Republic of China; 2Department of Respiratory and Critical Care Medicine,...

Full description

Bibliographic Details
Main Authors:	Zeng D, Zhang W, Chen X, Ou G, Huang Y, Yu C
Format:	Article
Language:	English
Published:	Dove Medical Press 2024-03-01
Series:	International Journal of COPD
Subjects:	copd ubiquitinase inhibitors p22077 airway inflammation nlrp3.
Online Access:	https://www.dovepress.com/inhibitory-effect-of-p22077-on-airway-inflammation-in-rats-with-copd-a-peer-reviewed-fulltext-article-COPD

Similar Items

Administration of USP7 inhibitor P22077 inhibited cardiac hypertrophy and remodeling in Ang II-induced hypertensive mice
by: Yu-Hui Gu, et al.
Published: (2022-10-01)

Role of inflammatory cells in airway remodeling in COPD
by: Wang Y, et al.
Published: (2018-10-01)

Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients
by: Patrizia Pignatti, et al.
Published: (2019-07-01)

Relationship between airway inflammation, small airway dysfunction, and frequency of acute exacerbations in patients with chronic obstructive pulmonary disease
by: Taha Taha Abdelgawad, et al.
Published: (2024-01-01)

An Insight into COPD Morphopathogenesis: Chronic Inflammation, Remodeling, and Antimicrobial Defense
by: Zane Vitenberga, et al.
Published: (2019-08-01)

Eosinophil Inflammation and Hyperresponsiveness in the Airways as Phenotypes of COPD, and Usefulness of Inhaled Glucocorticosteroids
by: Hiroaki Kume, et al.
Published: (2019-07-01)

Analysis of Airway Thickening and Serum Cytokines in COPD Patients with Frequent Exacerbations: A Heart of the Matter
by: Lin Y, et al.
Published: (2023-10-01)

Ubiquitin-specific protease 7 is a drug-able target that promotes hepatocellular carcinoma and chemoresistance
by: Wei Zhang, et al.
Published: (2020-01-01)

Establishment of Sunitinib-Resistant Xenograft Model of Renal Cell Carcinoma and the Identification of Drug-Resistant Hub Genes and Pathways
by: Xie Y, et al.
Published: (2021-12-01)

Olodaterol exerts anti-inflammatory effects on COPD airway epithelial cells
by: Nan Yang, et al.
Published: (2021-02-01)

Induced sputum in the management of COPD: clinical implications
by: A. Zanini, et al.
Published: (2015-12-01)

The Mechanisms of Resistin-Like Molecule-β-Mediated Airway Inflammation in Chronic Obstructive Pulmonary Disease via Autophagy
by: Che L, et al.
Published: (2023-08-01)

Systemic and Airway Epigenetic Disruptions Are Associated with Health Status in COPD
by: Ana I. Hernandez Cordero, et al.
Published: (2023-01-01)

Glucocorticoid Alleviates Mechanical Stress-Induced Airway Inflammation and Remodeling in COPD via Transient Receptor Potential Canonical 1 Channel
by: Wu X, et al.
Published: (2023-08-01)

Contribution of small airway inflammation to the development of COPD
by: Li Li, et al.
Published: (2024-03-01)

Dexamethasone attenuates airway inflammation in mouse models with allergic asthma
by: LIU Fen, HU Runfang, MAO Song, XU Min, SHI Wenjing, CHEN Ling
Published: (2023-03-01)

The Nicotinic Receptor Polymorphism rs16969968 Is Associated with Airway Remodeling and Inflammatory Dysregulation in COPD Patients
by: Lynda Saber Cherif, et al.
Published: (2022-09-01)

Effects of airway obstruction and hyperinflation on electrocardiographic axes in COPD
by: Peter Alter, et al.
Published: (2019-03-01)

The role of noninvasive methods in assessing airway inflammation and structural changes in asthma and COPD
by: K. Ahmad Dar, et al.
Published: (2015-12-01)

The acute wheezy adult with airways disease in the emergency department: a retrospective case-note review of exacerbations of COPD
by: Russell REK, et al.
Published: (2019-05-01)

The Role of Chitinases in Chronic Airway Inflammation Associated with Tobacco Smoke Exposure
by: Natalia Przysucha, et al.
Published: (2022-11-01)

Magnesium isoglycyrrhizinate inhibits airway inflammation in rats with chronic obstructive pulmonary disease
by: Ye Yang, et al.
Published: (2021-11-01)

Positive correlation of airway resistance and serum asymmetric dimethylarginine level in COPD patients with systemic markers of low-grade inflammation
by: Tajti G, et al.
Published: (2017-03-01)

Targeting IL-5 in COPD
by: Narendra DK, et al.
Published: (2019-05-01)

The role of the NLRP3 inflammasome in chronic inflammation in asthma and chronic obstructive pulmonary disease
by: Yaxin Wu, et al.
Published: (2022-12-01)

Biomarkers, Clinical Course, and Individual Needs in COPD Patients in Primary Care: The Study Protocol of the Stockholm COPD Inflammation Cohort (SCOPIC)
by: Lundh L, et al.
Published: (2022-05-01)

Small Airways Response to Bronchodilators in Adults with Asthma or COPD: A Systematic Review
by: Almeshari MA, et al.
Published: (2021-11-01)

Chronic Airways Assessment Test: psychometric properties in patients with asthma and/or COPD
by: Erin L. Tomaszewski, et al.
Published: (2023-04-01)

Airway Epithelium Senescence as a Driving Mechanism in COPD Pathogenesis
by: Georgia Bateman, et al.
Published: (2023-07-01)

Update on the roles of distal airways in COPD
by: N. Roche, et al.
Published: (2011-03-01)

Clinical significance of epithelial mesenchymal transition (EMT) in chronic obstructive pulmonary disease (COPD): potential target for prevention of airway fibrosis and lung cancer
by: Sukhwinder Singh Sohal, et al.
Published: (2014-12-01)

Inflammatory Endotype-Associated Airway Resistome in Chronic Obstructive Pulmonary Disease
by: Xinzhu Yi, et al.
Published: (2022-04-01)

Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD
by: Rachel L. Clifford, et al.
Published: (2018-03-01)

The Interplay Between Immune Response and Bacterial Infection in COPD: Focus Upon Non-typeable Haemophilus influenzae
by: Yu-Ching Su, et al.
Published: (2018-11-01)

Small airway inflammation in asthma
by: Christodoulopoulos Pota, et al.
Published: (2001-08-01)

Itaconate Suppresses the Activation of Mitochondrial NLRP3 Inflammasome and Oxidative Stress in Allergic Airway Inflammation
by: Qiu-Meng Xie, et al.
Published: (2023-02-01)

Dietary ω-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD
by: Sandra Rutting, et al.
Published: (2018-11-01)

FEATURES OF CYTOKINE-MEDIATED REGULATION OF FOCAL AND SYSTEMIC INFLAMMATION IN COPD
by: E. A. Surkova, et al.
Published: (2014-07-01)

Airway Microbiota-Host Interactions Regulate Secretory Leukocyte Protease Inhibitor Levels and Influence Allergic Airway Inflammation
by: Natalia Jaeger, et al.
Published: (2020-11-01)

Whole-Exome Sequencing of Bronchial Epithelial Cells Reveals a Genetic Print of Airway Remodelling in COPD
by: Adeline Germain, et al.
Published: (2022-07-01)