Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity

To intervene and control the toxic effects of the hazard factors using nature products is one of the research hotspots recently in the field of food safety. Curcumin, as a hydrophobic polyphenolic compound extracted from the traditional spice turmeric, has strong anti-inflammatory, anti-oxidation, a...

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Main Authors: Honglin LI, Yifang LI, Chi ZHANG, Hongyuan ZHOU, Ting GUO, Yuhao ZHANG, Liang MA
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2022-09-01
Series:Shipin gongye ke-ji
Subjects:
Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021090341
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author Honglin LI
Yifang LI
Chi ZHANG
Hongyuan ZHOU
Ting GUO
Yuhao ZHANG
Liang MA
author_facet Honglin LI
Yifang LI
Chi ZHANG
Hongyuan ZHOU
Ting GUO
Yuhao ZHANG
Liang MA
author_sort Honglin LI
collection DOAJ
description To intervene and control the toxic effects of the hazard factors using nature products is one of the research hotspots recently in the field of food safety. Curcumin, as a hydrophobic polyphenolic compound extracted from the traditional spice turmeric, has strong anti-inflammatory, anti-oxidation, anti-cancer, enhancing immunity and other activities. Recent studies have shown that curcumin can intervene some toxicities induced by mycotoxins such as Aflatoxin B1, Ochratoxin A, Zearalenone, Fumonisin B1 and Deoxynivalenol, thereby reducing damages and enhancing resistance in body. In this paper, the toxicities of main mycotoxins were briefly summarized at first. And then, the intervention effects and its related mechanism of curcumin on the mycotoxin-induced toxicities in the latest five years were emphatically elaborated, mainly from the aspects of reducing ROS production and lipid peroxidation, regulating related pathways and improving intestinal flora. Finally, the potential problems that to be urgently solved are discussed. Our review aimed at providing the theoretical bases for the in-depth development and utilization of curcumin in the health industry as well as to broaden the ideas for the research and development of other plant-derived functional components.
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spelling doaj.art-a9e79e4f7fa94463b96f6fa19ba3e1652022-12-22T04:14:44ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062022-09-01431749450010.13386/j.issn1002-0306.20210903412021090341-17Research Progress of Curcumin Intervening the Mycotoxin-induced ToxicityHonglin LI0Yifang LI1Chi ZHANG2Hongyuan ZHOU3Ting GUO4Yuhao ZHANG5Liang MA6College of Food Science, Southwest University, Chongqing 400715, ChinaCollege of Food Science, Southwest University, Chongqing 400715, ChinaCollege of Food Science, Southwest University, Chongqing 400715, ChinaCollege of Food Science, Southwest University, Chongqing 400715, ChinaCollege of Food Science, Southwest University, Chongqing 400715, ChinaCollege of Food Science, Southwest University, Chongqing 400715, ChinaCollege of Food Science, Southwest University, Chongqing 400715, ChinaTo intervene and control the toxic effects of the hazard factors using nature products is one of the research hotspots recently in the field of food safety. Curcumin, as a hydrophobic polyphenolic compound extracted from the traditional spice turmeric, has strong anti-inflammatory, anti-oxidation, anti-cancer, enhancing immunity and other activities. Recent studies have shown that curcumin can intervene some toxicities induced by mycotoxins such as Aflatoxin B1, Ochratoxin A, Zearalenone, Fumonisin B1 and Deoxynivalenol, thereby reducing damages and enhancing resistance in body. In this paper, the toxicities of main mycotoxins were briefly summarized at first. And then, the intervention effects and its related mechanism of curcumin on the mycotoxin-induced toxicities in the latest five years were emphatically elaborated, mainly from the aspects of reducing ROS production and lipid peroxidation, regulating related pathways and improving intestinal flora. Finally, the potential problems that to be urgently solved are discussed. Our review aimed at providing the theoretical bases for the in-depth development and utilization of curcumin in the health industry as well as to broaden the ideas for the research and development of other plant-derived functional components.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021090341curcuminmycotoxintoxicityintervention mechanismplant-derived
spellingShingle Honglin LI
Yifang LI
Chi ZHANG
Hongyuan ZHOU
Ting GUO
Yuhao ZHANG
Liang MA
Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity
Shipin gongye ke-ji
curcumin
mycotoxin
toxicity
intervention mechanism
plant-derived
title Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity
title_full Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity
title_fullStr Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity
title_full_unstemmed Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity
title_short Research Progress of Curcumin Intervening the Mycotoxin-induced Toxicity
title_sort research progress of curcumin intervening the mycotoxin induced toxicity
topic curcumin
mycotoxin
toxicity
intervention mechanism
plant-derived
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2021090341
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