The Immunoregulatory Function of Indoleamine 2, 3 Dioxygenase and Its Application in Allotransplantation

The Immunoregulatory Function of Indoleamine 2, 3 Dioxygenase and Its Application in Allotransplantation

Indolemine 2, 3-dioxygenase (IDO) is a cytosolic monomeric hemoprotein enzyme that catalyses tryptophan, the least available essential amino acid in the human body, to N-formylkynurenine, which in turn rapidly degrades to give kynurenine. IDO is expressed in different tissues, especially and promine...

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Bibliographic Details
Main Authors: Reza B. Jalili, Farshad Forouzeh, Mohammad Ali Bahar, Aziz Ghahary
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2007-12-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Allogeneic transplantation
Indoleamine 2
3 dioxygenase
T- lymphocytes
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/182

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