Molecular genetic aspects of sudden cardiac death: a literature review
Sudden cardiac death (SCD) continues to be a relevant and significant problem in modern medicine. Modern trends in medicine are associated with the widespread introduction of personalized, preventive strategies aimed at correcting risk factors for pathology, identifying predispositions to it and con...
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| Format: | Article |
| Jezik: | English |
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Siberian State Medical University (Tomsk)
2018-12-01
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| Serija: | Бюллетень сибирской медицины |
| Teme: | |
| Online dostop: | https://bulletin.ssmu.ru/jour/article/view/1994 |
| _version_ | 1827991535964127232 |
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| author | A. A. Ivanova V. N. Maksimov |
| author_facet | A. A. Ivanova V. N. Maksimov |
| author_sort | A. A. Ivanova |
| collection | DOAJ |
| description | Sudden cardiac death (SCD) continues to be a relevant and significant problem in modern medicine. Modern trends in medicine are associated with the widespread introduction of personalized, preventive strategies aimed at correcting risk factors for pathology, identifying predispositions to it and conducting prevention before the development of clinical symptoms. Nowadays, a huge number of studies of the molecular genetic basis of SCD are conducted. Studies of case-control design using routine methods of molecular genetic research continue to be popular. Research using modern, highly effective methods (sequencing of the next generation (NGS), full-genome associative studies (GWAS)) have become more frequent. The molecular genetic markers of SCD found in such studies can be used effectively to diagnose a predisposition to SCD and prevent its development in persons with known and unknown cardiac pathology. |
| first_indexed | 2024-04-10T01:06:40Z |
| format | Article |
| id | doaj.art-a9e7d06f97f04824b516693fe76797d1 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:06:40Z |
| publishDate | 2018-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-a9e7d06f97f04824b516693fe76797d12023-03-13T09:58:24ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842018-12-0117420922010.20538/1682-0363-2018-4-209-2201467Molecular genetic aspects of sudden cardiac death: a literature reviewA. A. Ivanova0V. N. Maksimov1Научно-исследовательский институт терапии и профилактической медицины (НИИТПМ), филиал Федерального исследовательского центра «Институт цитологии и генетики» Сибирского отделения Российской академии наук (ФИЦ ИЦиГ СО РАН); Новосибирский государственный медицинский университет (НГМУ)Научно-исследовательский институт терапии и профилактической медицины (НИИТПМ), филиал Федерального исследовательского центра «Институт цитологии и генетики» Сибирского отделения Российской академии наук (ФИЦ ИЦиГ СО РАН); Новосибирский государственный медицинский университет (НГМУ)Sudden cardiac death (SCD) continues to be a relevant and significant problem in modern medicine. Modern trends in medicine are associated with the widespread introduction of personalized, preventive strategies aimed at correcting risk factors for pathology, identifying predispositions to it and conducting prevention before the development of clinical symptoms. Nowadays, a huge number of studies of the molecular genetic basis of SCD are conducted. Studies of case-control design using routine methods of molecular genetic research continue to be popular. Research using modern, highly effective methods (sequencing of the next generation (NGS), full-genome associative studies (GWAS)) have become more frequent. The molecular genetic markers of SCD found in such studies can be used effectively to diagnose a predisposition to SCD and prevent its development in persons with known and unknown cardiac pathology.https://bulletin.ssmu.ru/jour/article/view/1994внезапная сердечная смертьgwasngsоднонуклеотидный полиморфизм |
| spellingShingle | A. A. Ivanova V. N. Maksimov Molecular genetic aspects of sudden cardiac death: a literature review Бюллетень сибирской медицины внезапная сердечная смерть gwas ngs однонуклеотидный полиморфизм |
| title | Molecular genetic aspects of sudden cardiac death: a literature review |
| title_full | Molecular genetic aspects of sudden cardiac death: a literature review |
| title_fullStr | Molecular genetic aspects of sudden cardiac death: a literature review |
| title_full_unstemmed | Molecular genetic aspects of sudden cardiac death: a literature review |
| title_short | Molecular genetic aspects of sudden cardiac death: a literature review |
| title_sort | molecular genetic aspects of sudden cardiac death a literature review |
| topic | внезапная сердечная смерть gwas ngs однонуклеотидный полиморфизм |
| url | https://bulletin.ssmu.ru/jour/article/view/1994 |
| work_keys_str_mv | AT aaivanova moleculargeneticaspectsofsuddencardiacdeathaliteraturereview AT vnmaksimov moleculargeneticaspectsofsuddencardiacdeathaliteraturereview |