Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetland
Abstract Viruses play important roles in ecosystems by interfering with the central metabolic pathways of the host during infection via the expression of auxiliary metabolic genes (AMGs), altering the productivity of ecosystems and thus affecting geochemical cycling. In this study, the genetic diver...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-28488-1 |
| _version_ | 1827984152725553152 |
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| author | Hang Yu Lingling Xiong Yanmei Li Yunlin Wei Qi Zhang Haiyan Li Wei Chen Xiuling Ji |
| author_facet | Hang Yu Lingling Xiong Yanmei Li Yunlin Wei Qi Zhang Haiyan Li Wei Chen Xiuling Ji |
| author_sort | Hang Yu |
| collection | DOAJ |
| description | Abstract Viruses play important roles in ecosystems by interfering with the central metabolic pathways of the host during infection via the expression of auxiliary metabolic genes (AMGs), altering the productivity of ecosystems and thus affecting geochemical cycling. In this study, the genetic diversity of phosphorus metabolism AMGs phoH, phoU and pstS was investigated by phylogenetic analysis, PCoA analysis, and alpha diversity analysis based on metagenomic data. It was found that the majority of the sequences were unique to Napahai plateau wetland. It was shown that the genetic diversity of phoH, phoU and pstS genes was independent of both habitats and host origins. In addition, the metabolic pathway of AMGs associated with the phosphorus cycling was identified based on metagenomic data. When phosphorus is deficient, virus utilizes AMGs to affect the metabolic pathway, contributing to higher phosphorus levels in the host and facilitating virus survival, replication, and propagation in the host cell. |
| first_indexed | 2024-04-09T22:56:25Z |
| format | Article |
| id | doaj.art-a9e8801566bb4a4ca0e0c13218ec6e77 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-09T22:56:25Z |
| publishDate | 2023-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-a9e8801566bb4a4ca0e0c13218ec6e772023-03-22T11:15:51ZengNature PortfolioScientific Reports2045-23222023-02-0113111110.1038/s41598-023-28488-1Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetlandHang Yu0Lingling Xiong1Yanmei Li2Yunlin Wei3Qi Zhang4Haiyan Li5Wei Chen6Xiuling Ji7Faculty of Life Science and Technology, Kunming University of Science and TechnologyFaculty of Life Science and Technology, Kunming University of Science and TechnologyFaculty of Life Science and Technology, Kunming University of Science and TechnologyFaculty of Life Science and Technology, Kunming University of Science and TechnologyFaculty of Life Science and Technology, Kunming University of Science and TechnologyMedical School, Kunming University of Science and TechnologyMedical School, Kunming University of Science and TechnologyMedical School, Kunming University of Science and TechnologyAbstract Viruses play important roles in ecosystems by interfering with the central metabolic pathways of the host during infection via the expression of auxiliary metabolic genes (AMGs), altering the productivity of ecosystems and thus affecting geochemical cycling. In this study, the genetic diversity of phosphorus metabolism AMGs phoH, phoU and pstS was investigated by phylogenetic analysis, PCoA analysis, and alpha diversity analysis based on metagenomic data. It was found that the majority of the sequences were unique to Napahai plateau wetland. It was shown that the genetic diversity of phoH, phoU and pstS genes was independent of both habitats and host origins. In addition, the metabolic pathway of AMGs associated with the phosphorus cycling was identified based on metagenomic data. When phosphorus is deficient, virus utilizes AMGs to affect the metabolic pathway, contributing to higher phosphorus levels in the host and facilitating virus survival, replication, and propagation in the host cell.https://doi.org/10.1038/s41598-023-28488-1 |
| spellingShingle | Hang Yu Lingling Xiong Yanmei Li Yunlin Wei Qi Zhang Haiyan Li Wei Chen Xiuling Ji Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetland Scientific Reports |
| title | Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetland |
| title_full | Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetland |
| title_fullStr | Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetland |
| title_full_unstemmed | Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetland |
| title_short | Genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in Napahai plateau wetland |
| title_sort | genetic diversity of virus auxiliary metabolism genes associated with phosphorus metabolism in napahai plateau wetland |
| url | https://doi.org/10.1038/s41598-023-28488-1 |
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