Lactobacillus improves the effects of prednisone on autoimmune hepatitis via gut microbiota-mediated follicular helper T cells

Lactobacillus improves the effects of prednisone on autoimmune hepatitis via gut microbiota-mediated follicular helper T cells

Abstract Background Autoimmune hepatitis (AIH) is a chronic, immune-mediated liver dysfunction. The gut microbiota and T follicular helper (Tfh) cells play critical roles in the immunopathogenesis and progression of AIH. We aimed to investigate the effect of gut microbiota combined with prednisone t...

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Bibliographic Details
Main Authors: Liang Ma, Liwen Zhang, Yun Zhuang, Yanbo Ding, Jianping Chen
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Cell Communication and Signaling
Subjects:
AIH
Tfh
Lactobacillus
Dendritic cells
MyD88
Online Access:https://doi.org/10.1186/s12964-021-00819-7

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