Immunization of Cattle With Recombinant Structural Ectodomains I and II of Babesia bovis Apical Membrane Antigen 1 [BbAMA-1(I/II)] Induces Strong Th1 Immune Response

Immunization of Cattle With Recombinant Structural Ectodomains I and II of Babesia bovis Apical Membrane Antigen 1 [BbAMA-1(I/II)] Induces Strong Th1 Immune Response

Both strong innate and adaptive immune responses are an important component of protection against intraerythrocytic protozoan parasites. Resistance to bovine babesiosis is associated with interferon (IFN)-γ mediated responses. CD4+ T cells and macrophages have been identified as major effector cells...

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Bibliographic Details
Main Authors: Amarin Rittipornlertrak, Boondarika Nambooppha, Anucha Muenthaisong, Nisachon Apinda, Pongpisid Koonyosying, Wanwisa Srisawat, Paweena Chomjit, Kanokwan Sangkakam, Veerasak Punyapornwithaya, Saruda Tiwananthagorn, Naoaki Yokoyama, Nattawooti Sthitmatee
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Veterinary Science
Subjects:
Babesia bovis
AMA-1
recombinant protein
Th1 immune response
cattle
vaccine
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.917389/full

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