Addition of oh8dG to Cardioplegia Attenuated Myocardial Oxidative Injury through the Inhibition of Sodium Bicarbonate Cotransporter Activity

Addition of oh8dG to Cardioplegia Attenuated Myocardial Oxidative Injury through the Inhibition of Sodium Bicarbonate Cotransporter Activity

The biomarker 8-hydroxy-2′-deoxyguanosine (oh8dG) is derived from oxidized nucleic acids or products of oxidant-mediated DNA damage. Enhanced sodium bicarbonate cotransporter (NBC) activity is caused by reactive oxygen species (ROS) production in ventricular myocytes. Thus, we hypothesized that card...

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Bibliographic Details
Main Authors:	Min Jeong Ji, Kuk Hui Son, Jeong Hee Hong
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	Antioxidants
Subjects:	cardioplegia oxidative stress 8-hydroxy-2′-deoxyguanosine sodium bicarbonate cotransporter reperfusion
Online Access:	https://www.mdpi.com/2076-3921/11/9/1641

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